Institute Of Oncology Ljubljana

This study tests whether adding a precise, high-dose radiation treatment (SBRT) after standard chemotherapy can help control locally advanced pancreatic cancer that cannot be removed by surgery. About 18 adults will receive chemotherapy first, then if the cancer hasn't spread, th…

This study tests a treatment called electrochemotherapy for women whose vulvar cancer has come back. It combines a chemotherapy drug with electric pulses to help the drug enter cancer cells more effectively. The goal is to shrink tumors and reduce the need for major surgery, whic…

This study is testing a highly precise radiation technique called SBRT for people with cancer that has spread to the spine. The goal is to deliver a strong dose of radiation while protecting nearby healthy tissue. Researchers will track side effects and how well the treatment con…

This study tests whether giving lidocaine during colon cancer surgery can reduce pain and the need for strong painkillers (opioids) afterward. It also looks at how quickly the bowel starts working again. About 100 adults having laparoscopic colon resection will be randomly assign…

This study tests whether giving lidocaine (a numbing medicine) or high-dose dexamethasone (a strong anti-inflammatory) during colon cancer surgery can improve the body's immune response and help patients recover better. About 100 adults having colon cancer surgery will be randoml…

This study looks at how well women with early-stage, hormone-positive breast cancer take their prescribed medications (aromatase inhibitors with or without abemaciclib). About 319 participants will be followed for 6 months to see if those on the combination therapy have lower adh…

This study looks at how much protein people with chronic intestinal failure need when they get nutrition through a vein at home. Researchers will measure how the body uses protein and check gut bacteria function. The goal is to make nutrition mixtures more personalized for each p…

This study is for people with high-risk early breast cancer, including inflammatory breast cancer. Researchers want to see if tiny clusters of tumor cells found in the blood can help predict how well treatment works and whether the cancer stays away. By studying these cell cluste…

This study looks at how chemotherapy affects thinking and memory in people with diffuse large B-cell lymphoma. Researchers will test cognitive function at the start, after the first chemo cycle, and one year later. They also analyze spinal fluid in some patients to find biologica…

This study looks at how common muscle loss (sarcopenia) is in people with gastrointestinal cancer. Researchers will use a simple questionnaire to screen patients before and during treatment. Those at risk will get extra nutritional support. The goal is to catch muscle loss early …

This study follows 368 colorectal cancer survivors aged 25-65 to see how their quality of life changes 6, 12, and 24 months after treatment. Researchers will use questionnaires to measure physical, mental, and social well-being, and look for late side effects linked to their spec…

This study looks at how electrochemotherapy—a treatment that uses electric pulses to help chemotherapy drugs enter tumor cells—changes the environment around melanoma skin tumors. Researchers will collect tissue samples from 150 adults with melanoma before and after treatment to …

This study looks at how many people with gastrointestinal cancer are at risk for sarcopenia, a condition where muscle mass and strength are lost. Sarcopenia can make cancer treatment harder and lower quality of life. Researchers will use a simple questionnaire (SARC-F) to screen …

This study is testing a web-based app that lets cancer patients report side effects from radiation therapy in real time. The goal is to catch problems early and improve care. About 30 adults with gynecologic, urologic, or breast cancer will use the app to answer simple questionna…

This study looks at how effective first-line immunotherapy is for people with metastatic melanoma in Slovenia. Researchers will track treatment response and safety, and analyze blood, stool, and body fluids to find markers that predict who benefits most. The goal is to improve pe…

This study is looking at how effective immunotherapy is as a first treatment for metastatic melanoma that has spread. Researchers will check if a marker called PD-L1, found in tumors and blood, can help predict who will respond well. About 100 adults with advanced melanoma will t…