Could lidocaine or dexamethasone improve colon cancer surgery recovery?
NCT ID NCT07432399
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial is testing whether giving lidocaine or high-dose dexamethasone during colon cancer surgery can improve the body's immune response and help patients recover better. 100 adults scheduled for colon cancer surgery will be randomly assigned to receive one of the two drugs or a placebo. The study measures inflammatory markers and pain levels to see if either drug reduces complications and speeds up recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lidocaine and dexamethasone
What this could lead to
If successful, this could point toward a simple, low-cost way to improve recovery and reduce complications after colon cancer surgery.
What could go wrong
This is an early Phase 2 trial with only 100 participants, so results may not apply to all patients. The study measures immune markers, not long-term outcomes, so benefits may not translate to real-world recovery.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Institute of Oncology Ljubljana
RECRUITINGLjubljana, 1000, Slovenia
Contact Phone: •••-•••-•••• Email: •••••@•••••