New pump could ease cancer pain without heavy drugs

NCT ID NCT07427888

Completed Symptom relief Sponsor: Institute of Oncology Ljubljana Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an implantable pump that delivers pain medicine directly into the spinal fluid for people with hard-to-treat cancer pain. Eight patients with advanced cancer and severe pain despite strong opioids took part. The goal was to see if the pump could provide better pain relief with fewer side effects than a standard pump placed under the skin.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: implantable intrathecal pump (device delivering analgesic medication directly into spinal fluid)
What this could lead to: If it works, this could offer a more effective and less side-effect-heavy way to manage severe cancer pain for patients who don't respond to standard treatments.
What could go wrong: This was a very small study (8 people) with no phase designation, so results may not apply broadly. The pump requires surgery and carries risks like infection or device malfunction.

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Conditions

The condition(s) this trial relates to.

cancer Cancer Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER PAIN NEOPLASM-RELATED PAIN

Contacts and locations

Locations

Institute of Oncology Ljubljana

Ljubljana, 1000, Slovenia

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