Immunotherapy before surgery may help remove stubborn colon cancer
NCT ID NCT06215677
First seen Jun 26, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This trial tests whether giving the immunotherapy drug camrelizumab before surgery can help completely remove T4 colon cancers that have a specific genetic feature (dMMR). These cancers often don't respond well to standard chemotherapy. The study will enroll 18 adults who will receive three doses of camrelizumab, then undergo surgery 2-3 weeks later. The main goal is to see if the cancer can be removed with clear margins and without damaging nearby organs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Camrelizumab (an immunotherapy drug)
- What this could lead to
- If successful, this could show that immunotherapy before surgery helps remove all cancer while sparing nearby organs in patients with this specific colon cancer type.
- What could go wrong
- This is a small, early-phase trial with only 18 participants, so results may not apply broadly. Immunotherapy can cause immune-related side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China
-
Peking Union Medical College Hospital
Beijing, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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