MISMATCH REPAIR DEFICIENCY
Clinical trials for MISMATCH REPAIR DEFICIENCY explained in plain language.
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New pill combo aims to boost immune attack on tough cancers
Disease control Recruiting nowThis study tests an experimental oral drug called Alintegimod combined with standard immunotherapies (ipilimumab and nivolumab) in people with advanced solid tumors like melanoma, lung, kidney, or liver cancer who have already tried other treatments. The goal is to see if the com…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Phase: PHASE1, PHASE2 • Sponsor: 7 Hills Pharma, LLC • Aim: Disease control
Last updated May 17, 2026 00:45 UTC
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Immunotherapy before surgery may help remove tough colon cancers without damaging nearby organs
Disease control Recruiting nowThis study tests whether giving immunotherapy before surgery can help completely remove T4 colon cancers that have a genetic feature called dMMR. These cancers often don't respond to standard chemotherapy. The trial aims to see if this approach increases the chance of clean surgi…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Blood test could spot colon cancers and lynch syndrome early
Diagnosis Recruiting nowThis study is testing a blood test (called a liquid biopsy) to see how well it can find colorectal cancer, advanced polyps, and Lynch syndrome-related cancers early. Researchers will enroll 1,200 people who have had a colonoscopy and take a blood sample to compare the test result…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Sponsor: San Raffaele University • Aim: Diagnosis
Last updated May 13, 2026 16:03 UTC
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AI could revolutionize how cancer patients find clinical trials
Knowledge-focused Recruiting nowThis study is testing whether an artificial intelligence (AI) tool can help match people with advanced cancer to the right clinical trials. Researchers will enroll up to 50,000 participants to see if the AI improves trial enrollment rates and patient outcomes. The goal is to make…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Sponsor: Massive Bio, Inc. • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC