MISMATCH REPAIR DEFICIENCY
Clinical trials for MISMATCH REPAIR DEFICIENCY explained in plain language.
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Sound waves and immunotherapy join forces against deadly brain tumor
Disease control Not yet recruitingThis early-phase study tests whether combining focused ultrasound with the immunotherapy drug pembrolizumab is safe and feasible for people with recurrent glioblastoma, a severe brain cancer. Only 8 participants with a specific genetic feature (mismatch repair deficiency) will be…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Phase: PHASE1 • Sponsor: Jennifer Leddon • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Could a drug combo replace the knife for some endometrial cancers?
Disease control Not yet recruitingThis study tests two immunotherapy drugs (iparomlimab and tuvonralimab) in 30 women with a specific type of endometrial cancer that is mismatch repair-deficient. The goal is to see if the treatment can make the cancer disappear or shrink enough to avoid surgery. Participants must…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Phase: PHASE2 • Sponsor: Women's Hospital School Of Medicine Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC