Blood test could spot colon cancer before it spreads

NCT ID NCT07450612

Recruiting now Diagnosis Sponsor: San Raffaele University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a blood test (called a liquid biopsy) to see if it can find colorectal cancer, pre-cancerous growths (adenomas), and cancers linked to Lynch syndrome at an early stage. Researchers will enroll 1,200 people who have already had a colonoscopy. The goal is to see how accurate the blood test is compared to standard methods, and whether it can also detect leftover cancer after treatment.

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Conditions

The condition(s) this trial relates to.

adenomatous colon polyp colon adenoma colonic disorder colonic neoplasm colorectal adenoma colorectal cancer colorectal neoplasm Colorectal Neoplasms, Hereditary Nonpolyposis Lynch syndrome Lynch syndrome 1 Lynch syndrome 2 mismatch repair cancer syndrome 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOMA COLON ADENOMA COLON POLYP COLO-RECTAL CANCER COLON ADENOMA COLON DISEASE COLON NEOPLASM COLORECTAL CANCER EPCAM GENE MUTATION LYN GENE MUTATION LYNCH SYNDROME LYNCH SYNDROME I LYNCH SYNDROME I (SITE-SPECIFIC COLONIC CANCER) LYNCH SYNDROME II MISMATCH REPAIR DEFICIENCY MISMATCH REPAIR GENE MUTATION MLH1 GENE MUTATION MSH2 GENE MUTATION MSH6 GENE MUTATION PMS2 GENE MUTATION

Contacts and locations

Locations

Dipartimento di Chirurgia Oncologica e Dipartimento di Oncologia Sperimentale Istituto Nazionale Tumori
NOT_YET_RECRUITING

Milan, MI, Italy
Gastronterology and Gastrointestinal Endoscopy Unit, IRCCS San Raffaele Hospital
NOT_YET_RECRUITING

Milan, Lombardy, 20132, Italy
Prof Giulia Martina Cavestro, MD PhD
NOT_YET_RECRUITING

Milan, Lombardy, 20132, Italy
San Raffaele Scientific Institute, Gastroenterology and Gastrointestinal Endoscopy Unit
RECRUITING

Milan, Lombardy, 20132, Italy

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