Blood test could spot colon cancer before it spreads

NCT ID NCT07450612

Recruiting now Diagnosis Sponsor: San Raffaele University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a blood test (called a liquid biopsy) to see if it can find colorectal cancer, pre-cancerous growths (adenomas), and cancers linked to Lynch syndrome at an early stage. Researchers will enroll 1,200 people who have already had a colonoscopy. The goal is to see how accurate the blood test is compared to standard methods, and whether it can also detect leftover cancer after treatment.

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Conditions

The condition(s) this trial relates to.

adenomatous colon polyp colon adenoma colonic disorder colonic neoplasm colorectal adenoma colorectal cancer colorectal neoplasm Colorectal Neoplasms, Hereditary Nonpolyposis Lynch syndrome Lynch syndrome 1 Lynch syndrome 2 mismatch repair cancer syndrome 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOMA COLON ADENOMA COLON POLYP COLO-RECTAL CANCER COLON ADENOMA COLON DISEASE COLON NEOPLASM COLORECTAL CANCER EPCAM GENE MUTATION LYN GENE MUTATION LYNCH SYNDROME LYNCH SYNDROME I LYNCH SYNDROME I (SITE-SPECIFIC COLONIC CANCER) LYNCH SYNDROME II MISMATCH REPAIR DEFICIENCY MISMATCH REPAIR GENE MUTATION MLH1 GENE MUTATION MSH2 GENE MUTATION MSH6 GENE MUTATION PMS2 GENE MUTATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Dipartimento di Chirurgia Oncologica e Dipartimento di Oncologia Sperimentale Istituto Nazionale Tumori
NOT_YET_RECRUITING

Milan, MI, Italy

Contact
Gastronterology and Gastrointestinal Endoscopy Unit, IRCCS San Raffaele Hospital
NOT_YET_RECRUITING

Milan, Lombardy, 20132, Italy

Contact

Contact

Contact

Contact Email: •••••@•••••

Contact

Contact
Prof Giulia Martina Cavestro, MD PhD
NOT_YET_RECRUITING

Milan, Lombardy, 20132, Italy

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
San Raffaele Scientific Institute, Gastroenterology and Gastrointestinal Endoscopy Unit
RECRUITING

Milan, Lombardy, 20132, Italy

Contact Email: •••••@•••••