Nutritional deficiency disease

This study tested three flavors of Supportan® drink (Tropical Fruits, Cappuccino, and Pineapple-Coconut) in 123 cancer patients undergoing chemotherapy, radiotherapy, immunotherapy, or targeted therapy. Patients drank two bottles daily for four weeks alongside their normal diet. …

This study looks at whether a vegan protein supplement made from buriti fruit, rice, and pea can improve body composition, flexibility, and balance in women aged 60 and older who regularly practice Tai Chi. Forty participants will receive either the supplement or a placebo for 12…

This study tests whether a daily multivitamin tablet can prevent vitamin and mineral deficiencies in people using GLP-1 drugs (like Ozempic or Saxenda) for weight loss. These drugs suppress appetite, which can lead to low nutrient intake. The trial will compare a multivitamin to …

This study tested two flavors of a high-energy, low-protein drink called Renalive® LP in 74 adults with chronic kidney disease stages 3b-5. Participants drank the formula as a meal replacement or supplement for 4 weeks. The goal was to see if the drink was suitable and helped mai…

Severe acute malnutrition affects millions of children worldwide and often leads to death after hospital discharge. This phase 3 trial tests whether giving a combination of antibiotics (rifampicin, azithromycin, isoniazid, and vitamin B6) for several weeks can lower the risk of d…

This trial tests whether a microbiota-directed food (MDF) can enhance immunity in severely malnourished children better than standard zinc with micronutrient powder and khichuri. Children aged 6-36 months who have recovered from acute infection will receive either MDF or the stan…

This study tests whether training mothers to measure their child's mid-upper arm circumference (MUAC) each week can spot severe malnutrition relapse sooner. Children aged 6 to 59 months who have recently recovered from severe acute malnutrition are enrolled. Mothers learn to use …

This study looks at whether specially designed nutritional supplements can improve thinking skills and emotional control in young children in Bangladesh who have moderate malnutrition. About 300 children aged 1 to 3 years receive either standard or enhanced nutritional supplement…

This study looked at whether teaching mothers about nutritious local foods can prevent malnutrition in children with sickle cell disease (SCD) in northern Nigeria. 146 children aged 6 to 18 months with SCD took part. Community health workers gave mothers special nutrition advice,…

This study tested whether giving babies one egg daily along with teaching parents about responsive feeding, nutrition, and hygiene can improve growth and development. 600 infants in Haiti were split into three groups: standard care, eggs only, or eggs plus the parenting program. …

This study tested whether daily cassava root and sesame seed granules, along with nutrition education, could improve the nutritional health of adults with HIV. Sixty-four participants took part, receiving either the granules plus education or education alone for 16 weeks. The goa…

This study tested a simple scoring system called RISQ to help healthcare workers quickly identify which severely malnourished children are most at risk of dying. Over 14,600 children aged 6 to 59 months in Chad took part. The goal was to see if using the RISQ system could lower d…

This study tested whether adding intravenous (IV) nutrition to standard oral supplements helps patients who had stomach cancer surgery recover better. 55 adults were randomly assigned to get either the combined nutrition or standard care. The main goal was to see if the combo app…

This study tested two new types of ready-to-use therapeutic foods (RUTFs) for treating severe and moderate acute malnutrition in children aged 6-59 months in Burkina Faso. The new RUTFs are made without peanuts or dairy, which could lower costs and reduce contamination risks. Ove…

This study looked at whether a protein-enriched food mix, made from local ingredients like cereals and soy, could improve the nutritional health of older adults living in the community. Researchers also included a simple daily exercise program. The goal was to find a practical, a…

This study tested whether a supplement called Striatin, made from snakehead fish extract, can help severely malnourished children gain weight and reduce inflammation. Thirty children received either Striatin or a placebo alongside standard nutritional therapy. Researchers measure…

This study tested whether special cookies made from soy, chickpea, and peanut flour could improve the health of malnourished children. Sixty children aged 3 to 10 years were split into two groups: one group ate the cookies daily for three months along with their regular diet, whi…

This study looked at whether a high-protein drink with added arginine can reduce problems like infections and slow bowel movement after colorectal surgery. It included 44 adults who were malnourished or at risk of malnutrition before their operation. Participants received either …

This study looked at whether taking creatine supplements can improve physical performance and body composition in people who follow a vegan diet. Twenty healthy, active vegans took either creatine or a placebo for four weeks while eating a vegan diet. Researchers measured sprint …

This study tested whether trained community health workers visiting pregnant women at home could improve health for both mothers and children in a rural area of South Africa. The program focused on supporting women with HIV, depression, or alcohol use, and on improving child grow…

This study tested whether a supplement made from the buriti fruit could help improve nutrition in people aged 90 and older. Forty participants took either the buriti supplement or a multivitamin daily for three months. Those taking the buriti supplement gained more weight, had a …

This study tested a 12-week health program for 60 older adults (65+) living in temporary container housing after the February 2023 earthquakes in Turkey. The program included personalized exercise, nutrition advice, and health counseling. Researchers measured changes in balance, …

This study looked at whether taking daily micronutrient supplements, with or without nutrition training and healthy lifestyle coaching, could improve the nutrition status and well-being of 150 young adults in Ghana. Participants were healthy university students aged 18-25. The ma…

This study looked at whether a special nutritional drink called Resource Diabet Plus can improve blood sugar and cholesterol levels in people with type 2 diabetes who are malnourished or at risk of malnutrition. Researchers reviewed medical records of 59 patients in Spain who too…

This phase 3 trial tested whether giving a special nutritional supplement (immunonutrition) before and after surgery could reduce infections in 311 patients with head and neck cancer. Participants were randomly assigned to one of three nutrition regimens. The main goal was to see…

This study tested whether taking a daily mix of dietary fiber and probiotics for 12 weeks could improve gut bacteria, immune function, and nutrition in 80 malnourished patients with advanced colorectal cancer. Participants received either the supplement or standard nutritional ad…

Nearly 60% of children with cancer become malnourished, which can lead to infections and worse outcomes. This pilot study tested three nutrition approaches—oral supplements, appetite-stimulating drugs, and tube feeding—in 19 children to see which best improved body composition an…

Hospitals use different definitions to diagnose undernutrition, and those definitions may label different numbers of patients as undernourished. This study compares the French HAS definition with the international GLIM definition in 260 adults hospitalized in diabetes-obesity, lu…

This study tested a short questionnaire called SEFI that asks children about their food intake to see if it can reliably identify those at risk for malnutrition in the hospital. Researchers compared SEFI results to standard growth measurements in 368 children aged 10-17. The goal…

This study involved 603 hospitalized children aged 2 to 59 months with severe acute malnutrition in Uganda and Zambia. Researchers tested various diagnostic methods—including chest X-rays, lab cultures, and symptom checks—to develop a score that helps doctors decide whether a chi…

This study tested whether muscle ultrasound can accurately detect undernutrition in 118 hospitalized patients aged 18-70. Researchers measured muscle thickness and quality using ultrasound and compared it to standard methods like bioelectrical impedance. If proven reliable, ultra…

Researchers are testing whether a high-protein diet before and after abdominal surgery helps older veterans recover better. Participants receive either 30 grams of protein three times a day for two weeks before and four weeks after surgery, or standard nutrition education with on…

Malnutrition is common in people having major surgery and links to worse outcomes. This study tests whether malnourished patients can receive intravenous nutrition, a mix of carbohydrates, fats, and protein, at an outpatient clinic for 5 to 10 days before surgery instead of being…

This trial tests whether adding a daily ration of small fish powder to the diets of infants aged 6 to 7 months improves their growth. Researchers in northern Cameroon will give 240 infants either the fish powder or a millet flour control for six months. The main goal is to see if…

This study tested whether a teacher-led hygiene campaign in primary schools in Lagos, Nigeria, could improve handwashing and prevent diarrhea, undernutrition, and pneumonia in children. Over 3,500 children from schools with clean water and toilets took part. Researchers measured …

This completed trial in Somalia tested whether giving families cash transfers, with or without extra nutrition education and additional cash, could prevent malnutrition in children and mothers. Over 3,300 families received monthly mobile cash for 6 months. Researchers measured wa…

This trial tests whether a special liquid nutrition formula, enriched with arginine, omega-3 fatty acids, and nucleotides, can reduce the frequency and severity of mouth sores (mucositis) in patients with head and neck or esophageal cancer undergoing chemoradiotherapy. Participan…

This Phase 2 trial is testing whether a daily supplement called Alii can reduce common side effects of hormonal birth control pills, like low energy, mood swings, and poor digestive health. Researchers will compare the supplement to a placebo in 68 women over 28 days. Participant…

This study tested whether silkworm pupa tablets can improve nutrition and reduce frailty in people who had surgery for stomach, colorectal, esophageal, or pancreatic cancer. 120 participants took the tablets for 3 months. Researchers measured weight, frailty, muscle mass, and qua…

This study tested whether a special numbing mixture called WALANT could reduce pain during central venous catheter (CVC) insertion better than standard lidocaine. Sixty-four trauma or dialysis patients were randomly assigned to receive either WALANT or lidocaine before the proced…

This study tested whether special snacks that change texture in the mouth could help improve nutrition in people with dementia. Ten participants living at home tried these snacks for a period of time. The goal was to see if the snacks were safe, acceptable, and easy to eat, with …

Many female athletes eat less carbohydrate than they need. Researchers want to know whether showing teen athletes their own metabolic test results changes their attitudes about carbohydrate more than a standard nutrition lesson does. Girls aged 13 to 19 at a sports academy join e…

Researchers are testing whether compounds from ultra-processed foods, like additives and advanced glycation end-products (AGEs), can be found in breast milk. They will measure AGE levels in milk samples from 300 healthy nursing mothers and track their diets with a 7-day food diar…

This study aims to identify biological markers of malnutrition by analyzing blood, saliva, and stool samples from 2,000 people, including those with malnutrition and healthy controls. Researchers will use advanced techniques to examine genetic, microbial, and metabolic profiles. …

This trial tests whether a brief online training program can improve how general practitioners and GP residents manage malnutrition and prescribe adapted physical activity in older adults. Doctors are randomly assigned to receive either malnutrition training or physical activity …

This study looks at whether adults with acute respiratory failure who need non-invasive ventilation (a breathing mask) are getting enough calories and protein. Researchers will track what each patient eats for five days after starting ventilation and compare it to recommended tar…

This observational study looks at whether muscle loss, measured on routine CT scans, is linked to 28-day survival in adults with cancer who are admitted to the intensive care unit (ICU). Researchers will compare muscle quality and nutritional scores between patients who survive a…

This study looked at whether the ratio of urea to creatinine in urine can help identify malnutrition in intensive care patients with brain injury. Malnutrition is common in the ICU and raises the risk of infections. Researchers measured this ratio in 309 adults and tracked six ty…

This study followed 75 malnourished patients after they left the hospital to see what kind of care they received and how their nutrition changed. Researchers also interviewed some patients and caregivers to learn about their understanding of malnutrition. The goal is to improve s…

This study looked at 30 undernourished teens with anorexia, aged 11 to 17, to see how taking oral phosphorus supplements for 6 months changes a hormone called FGF23, which helps control phosphate and vitamin D levels. The goal was to understand the link between phosphorus intake …

This study looked at whether a nutrition training program for family child care home providers could improve the food they serve to young children. 72 providers in Oklahoma took part, with half getting the nutrition program and half a comparison on environmental health. Researche…

This study looked at whether eating maize (corn) with extra zinc can improve gut health and nutrition in mothers and young children in Guatemala. 60 people took part. Researchers measured zinc levels, inflammation, and gut bacteria to see if the special corn made a difference.

This study tested a special gluten-free food guide designed to help children and teens (ages 5-18) with newly diagnosed celiac disease eat a healthier diet. Forty participants received either standard care or the new guide. Researchers measured diet quality and how well they foll…

This study looked at how malnutrition affects recovery in older adults (70+) who had broken bones like hips or shoulders. Researchers checked how common malnutrition was, tested different screening tools, and studied whether protein-rich diets helped improve outcomes. The goal wa…

This study tested a 4-month nutrition education program for 811 ethnic minority children aged 5-16 in Vietnam. The program included monthly lessons, videos, and support to improve eating habits and physical activity. Researchers compared these children to a control group to see i…

This study looked at how common malnutrition and muscle loss are in older adults in and out of Italian hospitals. Researchers checked 303 people aged 65 and older to understand links with diet, lifestyle, and health. The goal is to find better ways to prevent and treat malnutriti…

This study looked at whether three blood proteins (pre-albumin, retinol binding protein, and transferrin) can help detect early malnutrition in people with advanced nasopharyngeal cancer undergoing chemoradiotherapy. Researchers tracked 60 patients to see if these proteins change…

This study looked at 330 older adults (65+) who had cancer surgery to see if low albumin levels before surgery led to more complications. Researchers compared patients with low albumin to those with normal levels, tracking problems like infections, hospital stay length, and ICU n…

This study checks whether a questionnaire called SCREEN can accurately find nutrition risk in older adults (55+) who have mild cognitive impairment or dementia and live at home or in retirement homes. Researchers will compare SCREEN results to a dietitian's assessment and test if…

This study tested whether specially formulated foods made from locally available ingredients are acceptable to children with moderate acute malnutrition in Niger. Researchers developed 6 recipes meeting nutritional standards and evaluated them in 30 children aged 6-24 months. The…

This completed study tested a nutrition education program for older adults at risk of frailty in Taiwan and Japan. Researchers screened 30 elderly participants and provided motivational interviews and nutrition classes based on their needs. The study measured changes in chewing, …

This study tested whether home automation and remote monitoring can help elderly people (65+) with multiple chronic conditions live safely at home. Over 500 participants had their homes equipped with sensors that tracked health signs and sent alerts to doctors. The main goal was …

This study looked at whether giving a special liquid nutrition formula soon after C-section helps critically ill mothers in the ICU get enough protein and energy. 83 women participated, and researchers measured their protein intake and satisfaction with recovery. The goal was to …

This study explored why some people with latent (inactive) tuberculosis (TB) are more likely to develop active TB. Researchers looked at 626 people in South India to see how malnutrition, diabetes, and worm infections might change the body's response to TB. Participants gave bloo…

This study looked at whether two simple frailty questionnaires (G8 and VES-13) can predict serious side effects from chemotherapy in people 65 and older with gastrointestinal cancers. Researchers followed 72 patients receiving standard chemotherapy and checked their frailty, nutr…

This study in rural Nepal tested a nutrition education program to increase milk and animal food consumption among young children, adolescent girls, and women. Over 1,800 households participated, with some receiving training and activities. Researchers measured diet changes and gr…

This study tested whether offering extra support, like weekly phone calls or text messages, helps people in cardiac rehabilitation sign up for and use a Food is Medicine program. 84 adults from San Francisco were randomly assigned to receive navigation calls, texts, both, or neit…

This completed study involved 84 children with cerebral palsy to see if measuring mid-upper arm circumference can help assess their nutritional status. Standard height and weight measurements are often hard to get in these children due to motor and feeding difficulties. The resea…

This study looked at why some people infected with TB bacteria get sick while others don't. Researchers in India studied 120 household contacts of TB patients, comparing those who were malnourished or had parasitic worms. They provided food and deworming medication to see how the…

This study looked at whether giving extra nutrition through a vein in the arm (instead of a central line) helps people recover after colorectal surgery. 200 adults who had surgery for conditions like colorectal cancer or inflammatory bowel disease took part. The goal was to see i…

This study looked at over 3,300 households in Ethiopia to see which combination of food and nutrition programs works best. Families received different types of support, like savings groups, nutrition classes, or farming help. Researchers measured changes in food security, diet qu…

This study looked at how muscle energy works in 51 people with gastrointestinal cancer who were losing weight. The goal was to understand why cancer-related weight loss happens and find new ways to help. Researchers measured muscle cell energy use and fat storage, but this was an…

This study looked at whether a special hospital team and computer alerts could help doctors and nurses follow best practices for caring for malnourished children. Over 1,400 children and hospital staff took part. The goal was to see if better adherence to guidelines would lead to…

This study tested whether having a dietitian help patients with lung disease order meals during a hospital stay could improve their nutrition and reduce the chance of being readmitted after discharge. 41 patients at nutritional risk took part. Researchers measured daily food inta…

This study looked at whether serving foods that are easier to chew and swallow can help older adults in care homes eat more and faster. About 1 in 10 older adults in the UK are malnourished, and care home residents are especially at risk. Thirty residents tried two different meal…

This completed study looked at 102 children aged 2 to 8 who were hospitalized for at least 48 hours. Researchers wanted to understand if food pickiness and neophobia (fear of new foods) affect how much children eat in the hospital. They also examined whether a child's family back…

This study tested whether eating at least two eggs daily can help cancer survivors restore lost muscle and improve their quality of life after treatment. Only 2 people took part, making it a very small feasibility trial. Researchers measured protein intake, body weight, and overa…

This study looked at whether providing nutritional support to people being treated for tuberculosis (TB) improves their outcomes. Researchers compared TB patients in Benin, who receive food baskets and meals, to similar patients in Togo, who do not get systematic nutritional supp…

This completed study looked at 141 people being treated for tuberculosis (TB) to see if intestinal parasites or poor nutrition made their recovery harder. Researchers checked stool samples for parasites and measured weight gain and treatment success. Some participants received nu…

This study looked at whether eating beef every day for 30 days could improve thinking and visual skills in healthy young women. 80 women aged 18-40 took part, with one group eating beef and the other eating a plant-based protein. Researchers measured their performance on a 3D tra…

This study tested a nutrition training program for home care workers to help people with dementia eat better at home. Researchers worked with 139 participants, including people with dementia, their families, and care staff, to see if the program was practical and acceptable. The …

This study followed 193 patients at high risk of malnutrition who were admitted to a rehabilitation hospital. Researchers tracked whether specialized nutritional care affected hospital readmission rates, emergency visits, and other health outcomes three months after discharge. Th…

This study looked at whether one-on-one nutrition counselling could improve the nutritional status and quality of life of people aged 60 and older in Bahir Dar, Ethiopia. 210 older adults took part, receiving counselling based on health behavior models. The researchers measured c…

This completed study observed 206 children aged 1 to 5 in low-income communities in Colombia to assess malnutrition risk. Researchers measured height, weight, and diet, and also interviewed caregivers and health workers to understand local challenges. The goal is to gather inform…