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New numbing cocktail may ease pain of central line insertion

NCT ID NCT07299383

Completed Symptom relief Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special numbing mixture called WALANT could reduce pain during central venous catheter (CVC) insertion better than standard lidocaine. Sixty-four trauma or dialysis patients were randomly assigned to receive either WALANT or lidocaine before the procedure. Pain was measured using a visual scale. The goal was to see if WALANT offers a more comfortable and potentially safer alternative for this common but uncomfortable procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
WALANT solution (lidocaine, isotonic saline, sodium bicarbonate, epinephrine)
What this could lead to
If WALANT works better, it could offer a more comfortable and safer way to numb the area for central line placement, especially in patients at risk of bleeding.
What could go wrong
This is a small, completed study with only 64 participants. The results may not apply to all patients or settings, and the technique requires a 20-minute wait before the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

injury nutritional deficiency disease protein-energy malnutrition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIALYSIS CATHETER MALNUTRITION SEVERE TRAUMA (INCLUDING FRACTURES)

Contacts and locations

Locations

  • Atatürk University Research Hospital

    Erzurum, Erzurum, 25240, Turkey (Türkiye)

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