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Aortic valve stenosis

MONDO:0042981

Aortic valve stenosis (AVS) is a condition characterized by narrowing of the heart's aortic valve opening. This narrowing prevents the valve from opening fully, which obstructs blood flow from the heart into the aorta, and onward to the rest of the body. AVS can range from mild to severe. Signs and symptoms typically develop when the narrowing of the opening is severe and may include chest pain (angina) or tightness; shortness of breath or fatigue (especially during exertion); feeling faint or fainting; heart palpitations; and heart murmur. Individuals with less severe congenital AVS (present at birth) may not develop symptoms until adulthood. Individuals with severe cases may faint without warning. AVS can have several causes including abnormal development before birth (such as having 1 or 2 valve leaflets instead of 3); calcium build-up on the valve in adulthood; and rheumatic fever.

Also known as: AS, aortic stenosis, rheumatic aortic stenosis, rheumatic aortic valve stenosis, stenosed aortic valve, valvular aortic stenosis

508 clinical trials for this condition and its sub-types.

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Sub-types

Supravalvular aortic stenosis (3) Aortic valve atresia (0) Aortic valve dysplasia (0) Childhood aortic valve stenosis (0) Congenital aortic valve stenosis (0) Discrete subaortic stenosis (0) Subvalvular aortic stenosis (0)

Broader categories

Cardiovascular disorder (969) Disease (618) Heart disorder (273) Heart valve disorder (157) Vascular disorder (122) Aortic valve disorder (69) Aortic disorder (40) Human disease (14) Arterial disorder (8) Cardiac ventricle disorder (4)
Trials to join now! 213 Not yet recruiting 72 Not yet finished but already full! 92 Completed 122 Terminated 9
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