New stitch and glue combo aims to cut infections after bypass surgery

NCT ID NCT07507409

Not yet recruiting Disease control Sponsor: Unity Health Toronto Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new method for closing the breastbone after coronary artery bypass graft (CABG) surgery using special knotless barbed sutures and a skin adhesive. Researchers will compare 401 adults who receive this new closure to past patients who had standard closure. The goal is to see if the new method reduces wound infections, reopening, and other complications, and improves recovery and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Knotless barbed sutures (STRATAFIX™) and skin adhesive (DERMABOND™)
What this could lead to: If successful, this new closure method could reduce wound infections and complications after heart bypass surgery, leading to faster recovery and lower healthcare costs.
What could go wrong: This is a single-center study comparing results to past patients, not a randomized controlled trial, so differences in care over time could affect outcomes. The new materials may not perform better than standard methods.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder coronary artery disorder mediastinitis Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASE MEDIASTINITIS SUPERFICIAL STERNAL WOUND INFECTION SURGICAL SITE INFECTION

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