Could new hormone creams protect menopausal Women's hearts?

NCT ID NCT07394049

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large registry study will follow over 2,700 postmenopausal women aged 45-75 who use newer forms of hormone replacement therapy (creams, gels, sprays). The goal is to see if these modern delivery methods lower the risk of heart attacks, strokes, and other cardiovascular events. Researchers will track health outcomes over time to understand how these hormones affect heart health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hormone replacement therapy (creams, gels, sprays)

What this could lead to

If successful, this study could clarify whether newer HRT delivery methods lower heart disease risk in menopausal women.

What could go wrong

This is an observational registry, not a controlled trial, so it can show links but not prove cause and effect. Results may take years and could be inconclusive.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder cerebrovascular disorder coronary artery disorder peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinic for Cardiology, Angiology and Intensive Care at Charité Mitte Berlin

    Berlin, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospital Duesseldorf

    Düsseldorf, 40225, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••