University Hospital, Toulouse

This early-phase study tests a new stem cell treatment for people with Crohn's disease who have complex anal fistulas that haven't healed with standard care. The treatment uses donated fat-derived stem cells injected directly into the fistula to reduce inflammation and promote he…

This study is for postmenopausal women with osteoporosis who have been taking denosumab for at least two years and are now stopping it. Stopping denosumab can cause a rapid bone loss and increase fracture risk. The trial compares two strategies using zoledronic acid—one based on …

This study looks at whether placing a temporary balloon in the stomach, along with diet and exercise, can improve asthma control in obese adults whose asthma is not well managed by standard inhalers. About 84 participants will be randomly assigned to get the balloon plus lifestyl…

This study tests whether injecting stem cells from fat tissue into the fingers can heal painful, non-healing ulcers caused by scleroderma. About 32 adults with at least one active ulcer will receive either stem cells or a placebo. The goal is to see if the treatment helps ulcers …

This study looks at whether measuring a substance called D-lactate in spinal fluid can help doctors more accurately diagnose meningitis in patients who have a tube draining fluid from the brain. About 185 adults with a suspected infection will have their spinal fluid tested. The …

This study tests whether a special PET scan (18F-FES PET/CT) can find endometriosis lesions more accurately than MRI. It involves 20 women with endometriosis—some with high pain, some with low or no pain. The scan measures estrogen receptor activity in lesions, which may help doc…

This study explores whether measuring HIV drugs in hair can reliably detect when patients miss their medications. Currently, doctors rely on blood tests or patient reports, which can miss long-term non-adherence. Researchers will collect hair samples from 30 HIV-positive adults o…

This study looks at whether emergency doctors using a lung ultrasound in ambulances can more accurately diagnose the cause of severe shortness of breath. About 40 adults with serious breathing trouble will be included. The goal is to see if the ultrasound helps doctors choose the…

This study looks at whether using lung and heart ultrasound can help emergency doctors give the right treatment faster to older adults (over 65) with sudden breathing trouble. About 504 participants will be enrolled. The goal is to see if this approach reduces mismatched treatmen…

This study aims to improve how doctors tell if a small lung nodule is cancerous. Researchers will collect fluid left over from a routine scope procedure and analyze DNA in it for cancer signals. The goal is to see if this DNA test is more sensitive than current methods, potential…

This study tests the WHO's ICOPE program, which uses regular check-ups on mobility, memory, nutrition, vision, hearing, and mood to catch problems early. About 1,000 adults aged 65 and older who already show early signs of decline will either get the program or usual care. The go…

This study looks at whether a guided physical activity program can improve quality of life and reduce healthcare costs for women with breast cancer who are undergoing treatment like surgery, chemotherapy, or radiation. About 866 women will be randomly assigned to either the exerc…

This study explores whether an intensive two-week rhythmic dance program can improve motor, cognitive, and psychosocial learning in children with cerebral palsy. Six children aged 6 to 17 will participate in dance sessions and be assessed on personalized goals. The aim is to see …

This study tests whether a steroid injection into the knee's meniscus wall, guided by ultrasound, can quickly relieve pain from a degenerative meniscus tear. About 152 adults with knee pain that hasn't improved with standard treatments will receive either the steroid or a placebo…

This study tests whether a 6-month adapted physical activity program can improve endurance in children and teenagers with Marfan syndrome. About 30 participants aged 7 to 17 will take part. The program is designed to be safe and tailored to their condition, with the goal of makin…

This study tests whether a single educational session about the benefits of exercise can help people with Crohn's disease or ulcerative colitis (IBD) become more physically active. Researchers will track 71 adults in remission over 12 months to see if the session improves exercis…

This study tests if a single session of cardiac coherence—a guided breathing technique—can lower anxiety in patients before an MRI. Sixty adults with high MRI-related anxiety will be split into two groups: one does the breathing exercise, the other receives standard care. Researc…

This study tests whether three specialized wrap treatments—a therapeutic bath followed by heavy cream and occlusion—can reduce skin discomfort in people with moderate to very severe hereditary ichthyosis, a rare genetic condition causing scaly, painful skin. About 34 participants…

This study aims to create a large collection of blood samples and health data from 800 people with autoimmune skin diseases (like pemphigus, lupus, psoriasis, and eczema). Researchers will use these samples to find new biomarkers and better understand what causes these conditions…

This study aims to create a collection of blood and urine samples from 300 people with Marfan syndrome or related conditions. Researchers will use these samples to study how the disease works and find clues that might predict how it will progress. The study is for research only a…

This study is a national registry in France that collects information from adults newly diagnosed with immune thrombocytopenia (ITP) or autoimmune hemolytic anemia (AIHA). The goal is to better understand these rare blood disorders, track how they progress, and evaluate the real-…

This study talks to children aged 10 and older who had Guillain-Barré syndrome (GBS) two to five years ago. Researchers want to understand how they remember their illness and recovery, and whether they still feel tired, anxious, or sad. The goal is to learn how to better support …

This study aims to describe the typical care journey for 200 adults with head and neck cancer who need facial reconstruction using a bone flap from another part of the body. Researchers will analyze national health data to track hospital visits, treatments, and medications over t…

This study is creating a large collection of blood and other body fluid samples from 3,000 people with lung nodules or lung cancer. Researchers aim to identify new biomarkers that could help diagnose lung cancer earlier, predict outcomes, or guide treatment choices. Participants …

This study is testing a new method to measure allergy-related antibodies (IgE) in both blood and urine. Researchers want to see if this new technique works as well as the current standard test. About 1,376 people with allergies, aged 6 months and older, will provide blood and uri…

This study looks at whether adding a regular rhythm (like a beat) helps children with cerebral palsy or coordination disorders learn and remember a dance routine better. Researchers will compare how typically developing children and those with motor disorders perform a choreograp…

This study looks at whether people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD) experience more pain than others. iRBD is a strong early sign of Parkinson's disease, but pain in these patients has not been studied. Researchers will compare pain leve…

This study looks at whether a substance in urine, called S1P, can help doctors check for bladder overactivity in people with multiple sclerosis (MS). Bladder problems are common in MS, but the current best test is uncomfortable and invasive. Researchers will measure S1P levels in…

This study looks at how sleeping at high altitude (2,877 meters) affects the sleep of 32 employees at Pic du Midi. Researchers will compare sleep quality when workers sleep at home versus at the summit using special sleep tests. The goal is to better understand sleep problems in …

This study is creating a collection of blood and urine samples from 100 people with Noonan syndrome, including children aged 3 and older and adults. The samples will be used for research only, with strict confidentiality, to better understand how the condition progresses and what…

This study aims to uncover the molecular mechanisms behind kidney disease, immune disorders, and complications in organ transplant patients. Researchers will analyze blood and urine samples from 5,000 adults to find genetic and protein markers that predict disease progression or …

This study looks at how to better dose the drug acyclovir in people with obesity. Researchers will give the drug to 20 healthy volunteers with different body sizes, from normal weight to moderate obesity. They will measure drug levels in blood and urine to see if using lean body …

This study tests whether a monthly monitoring program (ICOPE) can detect early signs of decline in people over 70 with multiple myeloma. The goal is to prevent loss of independence. About 30 participants will use a digital app or chatbot to track their health. The main question i…

This study is creating a biobank—a collection of blood samples and health data—from 2,000 people with rheumatoid arthritis, psoriatic arthritis, spondyloarthritis, or osteoporosis. Researchers want to find biological markers that can predict how well a person will respond to trea…

This study looks at healthy adults over 60 to see if special brain scans and eye-tracking tests can predict who will keep a sharp memory and who may experience decline. Researchers will measure a tiny brain area called the locus coeruleus, which is one of the first places affecte…