New heat therapy could replace surgery for Hormone-Fueled hypertension
NCT ID NCT07470580
First seen Mar 13, 2026 · Last updated Jun 19, 2026 · Updated 16 times
Summary
This study compares two treatments for a condition called primary aldosteronism, where a small adrenal gland tumor causes high blood pressure. One treatment is laparoscopic surgery to remove the tumor; the other is radiofrequency ablation (RFA), which uses heat delivered through a needle to destroy the tumor. The goal is to see if RFA works as well as surgery to normalize blood pressure and hormone levels, with fewer side effects. About 134 adults with a confirmed adrenal adenoma will be randomly assigned to one of the two procedures.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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University Hospital of Toulouse
RECRUITINGToulouse, France
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiofrequency ablation (RFA) procedure
What this could lead to
If RFA works as well as surgery, patients could avoid an operation and have a quicker recovery with fewer complications.
What could go wrong
This is a relatively new use of RFA for this condition, and it may not be as effective as surgery in the long term. The trial is still recruiting, so results are not yet available.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.