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Stem cell shot aims to seal Crohn's fistulas

NCT ID NCT06636032

First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 35 times

Summary

This early study tests whether injecting stem cells from donated fat tissue can help heal complex anal fistulas in people with Crohn's disease who haven't gotten better with standard treatments. Nine adults will receive the stem cell injection and be followed for six months to check for side effects and signs of healing. The goal is to see if this approach is safe and worth testing in larger studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Toulouse Hospital

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

allogeneic adipose-derived mesenchymal stem cells (AdMSC)

What this could lead to

If it works, this could offer a new way to heal hard-to-treat anal fistulas in Crohn's disease without surgery or strong drugs.

What could go wrong

This is a very small, early-phase trial with only 9 people. It mainly checks safety, not effectiveness. The treatment may not work or could cause side effects.

Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.