Hair analysis could reveal hidden HIV pill skipping
NCT ID NCT07062614
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether measuring HIV drugs in hair can reliably show if patients are taking their medication as prescribed. Researchers will collect hair and blood samples from 30 HIV patients who are known to be compliant. The goal is to see if hair can be a simple, non-invasive tool to detect missed doses, which is hard to do with current blood tests.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
patients with HIV and receiving antiretroviral therapy with Emtricitabine or Lamivudine.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient living with HIV * Patient receiving stable antiretroviral therapy (i.e., no change in treatment strategy or dosage regimen) for at least 6 months. * Patient receiving antiretroviral therapy based on emtricitabine or lamivudine. * Patient identified as compliant based on patient follow-up data: (i) patient's reported adherence to the infectious disease physician (i.e., simple self-report), (ii) virological data (i.e., absence of blips in the last 18 months), (iii) pharmacological data (i.e., plasma antiretroviral concentrations within the expected range) if concentrations were previously measured as part of the patient's follow-up. * Patient agreeing not to cut their hair to less than 6 cm of remaining length during the 6 months of the study. * Patient agreeing to have their hair sampled at the end of the 6 months. * Patients over 18 and under 70 years of age. * Individuals who have not objected. * Individuals enrolled in the French Health Insurance Exclusion Criteria: * Pregnant women. * Patients planning to color/bleach their hair in the next 6 months. * Patients planning to have their hair straightened/restyled in the next 6 months. * Persons under judicial protection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Infectious and Tropical Diseases Department, Purpan University Hospital, Toulouse Place du Docteur Baylac
RECRUITINGToulouse, 31059, France
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