HIV (HUMAN IMMUNODEFICIENCY VIRUS)

This early-stage study tests whether two experimental antibodies (MGD014 and MGD020) are safe in people with HIV who are on standard antiretroviral therapy. Some participants will also take a drug to wake up hidden HIV, and others will pause their regular HIV meds for up to 8 wee…

This study tests a program called Project YES+ for youth aged 15-21 living with HIV in Zambia. It combines peer mentoring with a mental health approach to reduce stigma from HIV, violence, and mental health issues. The goal is to help them stick with their HIV treatment and impro…

This study tests whether resmetirom, a drug already approved for other liver conditions, can safely reduce liver fat in people with HIV who also have a fatty liver disease called MASLD. About 120 adults with HIV on antiretroviral therapy will take either the drug or a placebo dai…

This study tests whether empagliflozin, a drug used for diabetes, can help people with HIV who are overweight or obese lose weight and improve their metabolism. About 66 adults with HIV on a specific type of antiretroviral therapy will take either the drug or a placebo for 6 mont…

This study tests whether giving guaranteed income to people with HIV recently released from jail helps them stay in HIV care and keep the virus under control. 33 participants will receive money as a lump sum, monthly payments, or choose their preference. Researchers will measure …

This study explores whether a strand of hair can reliably show if people with HIV are taking their daily medication. Researchers will measure drug levels in hair segments from 30 compliant patients to see if the test can spot missed doses. If successful, it could offer a simple, …

This study looks at whether giving HIV prevention pills (PrEP) at the same time as opioid addiction treatment in pharmacies works well. About 350 HIV-negative people who are at risk for HIV and already getting opioid therapy will take part. The goal is to see if this approach mak…

This study looks at whether traditional healers in rural Uganda can offer HIV tests to children ages 18 months to 5 years. Researchers want to see if caregivers accept testing from a healer versus going to a health center. About 400 children will take part, and the goal is to fin…

This study aims to find out if people with tuberculosis (TB) who have no symptoms can pass the infection to others. Researchers will follow about 6,770 participants, including those with HIV, and use advanced genetic testing to track how TB spreads. The goal is to better understa…

This study tests whether a program called TransAction helps transgender women in Ho Chi Minh City improve their HIV prevention and care. Participants will attend individual counseling, skill-building groups, and social events. The goal is to see if this approach helps more people…