New study aims to prevent bone fractures after osteoporosis drug switch
NCT ID NCT06767150
First seen Jan 05, 2026 · Last updated Apr 29, 2026 · Updated 15 times
Summary
This study is for postmenopausal women with osteoporosis who have been taking denosumab for at least two years and are now stopping it. Stopping denosumab can cause a rapid bone loss and increase fracture risk. The trial compares two strategies using zoledronic acid—one based on individual bone markers and one standard approach—to see which better maintains bone density. About 200 women will participate, and the goal is to find the safest way to transition off denosumab.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Amiens Hospital
RECRUITINGAmiens, France
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Bordeaux Hospital
RECRUITINGBordeaux, France
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Cahors Hospital
RECRUITINGCahors, France
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Cochin Hospital
RECRUITINGParis, France
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Dax Hospital
RECRUITINGDax, France
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Lariboisiere Hospital
RECRUITINGParis, France
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Le Mans Hospital
RECRUITINGLe Mans, France
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Lille Hospital
NOT_YET_RECRUITINGLille, France
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Limoges Hospital
RECRUITINGLimoges, France
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Marseille Hsopital
RECRUITINGMarseille, France
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Montpellier Hospital
RECRUITINGMontpellier, France
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Nice Hospital
RECRUITINGNice, France
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Orléans Hospital
RECRUITINGOrléans, France
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Poitiers Hospital
RECRUITINGPoitiers, France
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Rennes Hospital
RECRUITINGRennes, France
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Saint Etienne Hospital
RECRUITINGSaint-Etienne, France
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Toulouse Hospital
RECRUITINGToulouse, France
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Conditions
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