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Baby jaundice may leave lasting marks on teeth, new study investigates

NCT ID NCT06506734

Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how common tooth staining is in children who had very high bilirubin levels (jaundice) early in life. Researchers will check 120 children with certain liver conditions to see if their teeth are discolored and whether that affects their daily life. The goal is to gather evidence to help families get dental care covered by insurance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children aged 12 to 18 years

Ages

12 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A patient with biliary atresia, progressive familial intrahepatic cholestasis, or Alagille syndrome * Patient or legal representative not opposed to participating in this research. Exclusion Criteria: * Inability to understand and respond to quality of life questionnaires

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Conditions

The condition(s) this trial relates to.

Alagille syndrome biliary atresia Cholestasis, progressive familial intrahepatic 1 hyperbilirubinemia progressive familial intrahepatic cholestasis Stomatognathic Diseases Tooth Discoloration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    9 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, FHU Hépatinov

    RECRUITING

    Paris, France

  • Assistance Publique-Hôpitaux de Paris, Hôpital Bretonneau, Paris

    RECRUITING

    Paris, France

  • Assistance Publique-Hôpitaux de Paris, Hôpital Necker

    RECRUITING

    Paris, France

  • Hospices Civils de Lyon

    RECRUITING

    Lyon, France

  • University Hospital Bordeaux

    RECRUITING

    Bordeaux, France

  • University Hospital Lille

    RECRUITING

    Lille, France

  • University Hospital Marseille

    RECRUITING

    Marseille, France

  • University Hospital Rennes

    RECRUITING

    Rennes, France

  • University Hosptial Caen

    RECRUITING

    Caen, France

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