Brain scans reveal secrets of learning in memory loss patients
NCT ID NCT07191197
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 150 people with memory problems caused by damage to specific brain areas (medial temporal lobe). Researchers will use MRI scans and memory tasks to see how these patients can still learn new information. The goal is to understand which brain parts are important for learning, not to test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal which brain areas are key for learning new information, potentially guiding future therapies for memory disorders.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly help patients. Results may not apply to all types of memory loss.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged between 18 and 70 years * Living in France since less than 20 years, being able to understand the French language, and have basic cultural knowledge as evaluated in classical clinical consultation * Written agreement to participate in the study * Intellectual capacities compatible with the cognitive tasks and signing of consent * Affiliation to the French social security system * For patients: bilateral brain lesion of the medial temporal lobe or the extended hippocampal system Exclusion Criteria: * Subjects under the age of 18 or over 70 * Contraindications for MRI (examples: wearers of a pacemaker or cardiac defibrillator, implanted equipment activated by an electrical, magnetic or mechanical system, wearers of haemostatic clips for intracerebral aneurysms or carotid arteries, wearers of orthopedic implants, claustrophobic) * Refusal to be informed of an anomaly detected during the MRI
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital of Caen
ACTIVE_NOT_RECRUITINGCaen, France
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University Hospital of Toulouse
RECRUITINGToulouse, France
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