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New PET tracer could spot brain inflammation in autoimmune encephalitis

NCT ID NCT07488117

First seen Mar 24, 2026 · Last updated Jun 22, 2026 · Updated 12 times

Summary

This study tests whether a special PET scan tracer called [18F]-DPA-714 can detect brain inflammation in people with autoimmune encephalitis (AE). Researchers will compare scans from 40 newly diagnosed AE patients to healthy volunteers. If the tracer works well, it could become a new tool for diagnosing and tracking this rare brain condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital

    RECRUITING

    Toulouse, France

    Contact Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]-DPA-714 (a radioactive tracer for PET imaging)

What this could lead to

If successful, this imaging method could help doctors diagnose and monitor brain inflammation in autoimmune encephalitis more accurately.

What could go wrong

This is a small early-phase study (40 people) focused on imaging, not treatment. The tracer may not clearly distinguish patients from healthy controls.

Conditions

The condition(s) this trial relates to.

autoimmune disorder of the nervous system

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.