Autoimmune encephalitis (AE)
Clinical trials for Autoimmune encephalitis (AE) explained in plain language.
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Could fewer plasma exchange sessions be just as effective for kids with brain inflammation?
Disease control Recruiting nowThis trial tests whether plasma exchange (a blood-cleaning procedure) given every other day works as well as daily sessions for children with autoimmune encephalitis, a condition where the immune system attacks the brain. The study involves 22 children who are randomly assigned t…
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Sponsor: Menoufia University • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Could a new Antibody-Lowering drug ease autoimmune brain inflammation?
Disease control Recruiting nowThis Phase 2 trial tests efgartigimod PH20 SC, a drug that lowers harmful antibodies, in 170 adults and teens with autoimmune encephalitis (AIE). Participants receive either the drug or a placebo, and researchers measure changes in disability and symptoms over up to 3 years. The …
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Phase 2 • Sponsor: argenx • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Engineered immune cells take on multiple sclerosis and other autoimmune brain diseases
Disease control Recruiting nowThis early-phase study tests a new treatment called RD06-05, which uses specially engineered immune cells (CAR-T cells) to target and calm the immune system in people with neurological autoimmune diseases like multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinat…
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Early phase 1 • Sponsor: Tongji Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Experimental cell therapy takes aim at Hard-to-Treat autoimmune diseases
Disease control Recruiting nowThis early-phase trial is testing a new cell therapy called QH103 for people with severe autoimmune diseases like multiple sclerosis and myasthenia gravis that haven't responded to standard treatments. The therapy uses specially engineered immune cells to target and attack the fa…
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Phase 1 • Sponsor: Tongji Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New PET tracer could spot brain inflammation in autoimmune encephalitis
Diagnosis Recruiting nowThis study tests whether a special PET scan tracer called [18F]-DPA-714 can detect brain inflammation in people with autoimmune encephalitis (AE). Researchers will compare scans from 40 newly diagnosed AE patients to healthy volunteers. If the tracer works well, it could become a…
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Phase 2 • Sponsor: University Hospital, Toulouse • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC