New breathing device could help ALS patients clear their lungs
NCT ID NCT05819931
First seen May 24, 2026 · Last updated Jun 20, 2026 · Updated 7 times
Summary
This pilot study tests a mechanical in-exsufflator (MIE) device that helps ALS patients cough more effectively by pushing air in and then pulling it out. The goal is to see if daily use for four weeks can maintain or improve lung function. The study will enroll 36 adults with ALS who have a weak cough.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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SLA Center - Purpan University Hospital Toulouse, FRANCE
RECRUITINGToulouse, Occitanie, 31000, France
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mechanical In-Exsufflator (MIE) device
What this could lead to
If it works, this device could help ALS patients clear their airways more easily, potentially slowing respiratory decline and improving quality of life.
What could go wrong
This is a small pilot study with only 36 participants, so results may not apply to all ALS patients. The device is meant to ease symptoms, not stop or reverse the disease.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.