PREDIABETES

This study looked at whether taking fish oil and doing high-intensity interval training (HIIT) could lower inflammation in people with obesity. 129 overweight or obese adults with prediabetes and high triglycerides took part. The goal was to see if the combination improves gut ba…

This study tested whether regularly donating blood to lower iron levels can improve blood sugar control and reduce fatty liver in people with prediabetes or diabetes. 132 adults aged 40-75 were assigned to either donate blood or a control group. Researchers measured changes in bl…

This study looked at whether a low-carb, high-fat ketogenic diet with fewer calories can lower inflammation and improve insulin resistance in adults with prediabetes and obesity. Ninety participants aged 18-40 were split into three groups: a keto diet, a normal diet with fewer ca…

This study tested whether using portable air cleaners at home can improve blood sugar control and reduce inflammation in adults with prediabetes. 150 participants used either real or sham air cleaners for 4 weeks. Researchers measured changes in blood sugar patterns and inflammat…

This study tested a weekly injection of semaglutide (2.4 mg) in 207 adults with obesity and prediabetes. Participants received either the drug or a placebo for 12 months, plus lifestyle advice. The goal was to see how much weight they lost and whether their blood sugar returned t…

This study tested whether a flexible lifestyle program could help people with obesity and related health issues like insulin resistance, diabetes, or high blood pressure. Forty adults first received either nutrition or exercise counseling, and those who didn't improve enough afte…

This study looked at whether bread made from watermelon rind could improve heart health in 120 adults with mild to moderate heart issues. Participants were between 35 and 65 years old and had conditions like high blood pressure, unhealthy cholesterol levels, or pre-diabetes. The …

This study tested whether the diabetes drug empagliflozin can be used in people with prediabetes to help prevent the condition from progressing to full-blown diabetes. Sixty veterans with prediabetes took either empagliflozin or received standard lifestyle advice for 12 weeks. Th…

This study tested whether adding green tea extract to standard metformin treatment can improve insulin resistance in obese children aged 10-18 with prediabetes. 90 participants were split into two groups: one received metformin alone, the other added green tea extract three times…

This study tested whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes who recently had a heart attack or stroke. Researchers used a special PET scan to measure inflammation in the blood vessels. 115 participants were randomly …

This study tested whether a supplement called nicotinamide mononucleotide (NMN) can improve how the body handles sugar in people with prediabetes. Researchers gave NMN to 56 adults with higher-than-normal blood sugar and measured changes in insulin sensitivity and glucose toleran…

This study looked at whether a gut bacterium called Akkermansia muciniphila and a natural compound called berberine can help manage prediabetes in obese adults. 110 overweight or obese people with prediabetes were given either the bacterium, berberine, or a placebo for 12 weeks. …

This pilot study tested two approaches to improve metabolic health in Black adults with stage 1 obesity and conditions like high blood pressure or prediabetes. Participants received either weight-focused or weight-neutral health coaching for 7 weeks. The goal was to see if a larg…

This study tested whether a 6-week mindfulness program could help teens at risk for type 2 diabetes by reducing depression and insulin resistance. 120 teens aged 12-17 with overweight, a family history of diabetes, and elevated depression symptoms took part. They were randomly as…

This study tested whether taking a synbiotic supplement (a mix of probiotics and prebiotics) for 6 months can improve blood sugar control, reduce inflammation, and improve body composition in adults with prediabetes or type 2 diabetes. The trial included 64 participants from Saud…

This study tested a mobile platform designed for people with prediabetes. It combines educational games, lifestyle challenges, and community interaction to encourage healthy habits. Sixty participants used the platform, and researchers tracked their diet, exercise, and blood suga…

This study looked at whether a prebiotic fiber called inulin can improve how the body handles sugar and fat in adults with prediabetes. Twenty-two participants took either inulin or a placebo daily for 6 weeks while eating a controlled diet. Researchers measured insulin sensitivi…

This study tested a special nutritional supplement containing apple extract, chromium, zinc, magnesium, and cinnamon in 21 people with prediabetes. The goal was to see if it could help control blood sugar spikes after meals. The supplement is designed to be taken long-term to man…

This study looked at 120 shift workers with prediabetes or type 2 diabetes who were overweight. Participants followed one of three low-calorie diets for 12 weeks, each with different amounts of protein at dinner. The goal was to see which diet best improved blood sugar, insulin, …

This study tested a virtual health program for African immigrants aged 25-75 who had at least two risk factors like diabetes, high blood pressure, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over 6 months. The program was deliv…

This study tested a lifestyle guide called GEM (Glycemic Excursion Minimization) along with a continuous glucose monitor and a FitBit in 61 adults with prediabetes. The goal was to see if these tools could help lower blood sugar spikes and improve overall glucose control. Partici…

This study looked at whether doing aerobic exercise at home with a heart rate monitor (tele-exercise) works as well as supervised hospital-based exercise for people with prediabetes. 42 adults with prediabetes walked for 30 minutes, 5 days a week for 3 weeks. The goal was to see …

This study looked at whether adding dapagliflozin to metformin helps people with prediabetes or type 2 diabetes and severe obesity lose more weight than metformin alone. About 160 participants took either both drugs or just metformin for up to 12 months. The main goal was to see …

This study looked at whether a 3-month supervised exercise program can improve blood sugar, body fat, and fitness in sedentary men aged 35-65 with type 2 diabetes, prediabetes, or overweight. Participants exercised at a fitness center under supervision. The goal was to see how di…

This study looked at whether eating only within a 10-hour window each day helps overweight adults aged 50 to 75 with prediabetes lose fat and improve their metabolism. 57 participants either followed the 10-hour eating plan or their usual 13-hour eating pattern, while tracking th…

This study looked at whether adding a nurse trained in diabetes care to the treatment team helps breast cancer patients with diabetes or prediabetes manage their blood sugar during cancer therapy. Researchers split 74 patients into two groups: one worked with the diabetes nurse, …

This pilot study tested a mobile app and wearable devices to give personalized diet and activity advice to 27 adults with type 2 diabetes or prediabetes. The goal was to see if the app could help them improve their blood sugar levels and make healthier food choices. The study als…

This study tested a new device called the Cmate blood glucose analyzer, which measures blood sugar without needing a finger prick. Researchers compared its readings to standard blood tests in 40 healthy, pre-diabetic, and type 2 diabetic adults. The goal was to see if this non-in…

This study tested whether computer analysis of voice recordings can detect type 2 diabetes in adults. Over 7,300 participants recorded themselves reading and answering questions online. A subset also provided blood samples to compare voice predictions with standard HbA1c tests. T…

This study tested whether a lifestyle modification program—including diet advice, exercise plans, and mobile reminders—could reduce the risk of prediabetes progressing to type 2 diabetes. 124 adults with prediabetes participated. The goal was to see if simple, everyday changes co…

This completed study compared two versions of the Diabetes Prevention Program in 304 overweight adults with prediabetes. One group followed the standard lower-calorie, lower-fat diet, while the other tried a very low-carbohydrate diet. Researchers measured changes in blood sugar …

This study tested a year-long online program to help adults aged 40-70 who are at risk for heart disease become more active. Participants received a fitness tracker, online coaching, and educational sessions. The goal was to see if this approach could increase daily steps and hel…

This study tested a program to help Chinese immigrants with prediabetes prevent type 2 diabetes. Participants received weekly videos on diabetes prevention and access to fresh vegetables from a community farm. The goal was to see if this approach could help people lose weight and…

This study tested a diabetes prevention program designed for college students at high risk for type 2 diabetes, especially those facing food or financial insecurity. About 80 UCLA undergraduates with prediabetes or high risk were randomly assigned to either a tailored 19-session …

This study looked at whether helping people with pre-diabetes get more sleep each night can improve their blood sugar control and lower their risk of developing type 2 diabetes. About 150 adults who slept less than 6.5 hours per night were randomly assigned to either extend their…

This study tested whether a habit-formation smartphone app could help adults with prediabetes stay engaged in the National Diabetes Prevention Program. Researchers compared how many classes people attended and how long they stayed in the program between those who used the app and…

This study tested whether a fully automated digital program could help people with prediabetes lose weight and lower their blood sugar as effectively as a program led by a human coach. About 368 adults with prediabetes and overweight took part. The goal was to see which approach …

This study looked at whether limiting when you eat (time-restricted eating) can improve blood sugar control and heart health in adults with prediabetes. 108 participants were assigned to eat only between 8am-3pm, 1pm-8pm, or a normal 12-hour eating window for 8 weeks. All meals w…

This study tested whether watching AI-generated health education videos while wearing a continuous glucose monitor (CGM) helps people with prediabetes control their blood sugar. Thirty adults with prediabetes took part. The goal was to see if this approach could prevent progressi…

This study tested a program that combines counseling, mobile health tools, and school/community support to prevent and manage type 2 diabetes and high blood pressure in adults, while also improving health in their children. Over 1,200 families from four European countries took pa…

This study tested a new version of the National Diabetes Prevention Program (NDPP) that lets participants set their own goals. 214 adults with prediabetes took part. The goal was to see if this flexible approach could lower blood sugar levels and help more people return to normal…

This study tested whether daily text messages and financial incentives could motivate overweight teens and young adults with prediabetes or type 2 diabetes to be more physically active. Participants wore a Fitbit and received texts with personalized goals and either a small rewar…

This study looked at whether a collagen supplement can improve blood sugar levels after a meal in people with normal blood sugar or prediabetes. Thirty adults took either collagen or a placebo and then had their blood sugar, insulin, and digestion tracked. The goal was to see if …

This study looked at whether a program called Vivo can improve leg strength and blood sugar levels in older adults with prediabetes. 74 sedentary people aged 60 and older with prediabetes took part. Over 12 weeks, researchers measured how many times they could stand from a chair …

This study tested whether taking Nextida-GC (a collagen peptide) or whey protein before breakfast can lower blood sugar spikes after eating. Thirty-two healthy adults, some with prediabetes, drank the supplement 30 minutes before, 10 minutes before, or with a standard breakfast. …

This study looked at whether a live, online strength training program called Vivo is practical and liked by older adults with prediabetes. 28 sedentary people aged 60 and older took part in 12 weeks of twice-weekly workouts. The program was well-attended and participants reported…

This study tested a mindfulness program for 30 teens aged 12-18 with prediabetes or type 2 diabetes. The goal was to see if the program was practical and liked by teens, and to explore any effects on health measures like blood sugar. The approach involved group sessions and quest…

This study looked at how short periods of low oxygen (from holding your breath) affect blood sugar levels after drinking a sugary drink. Researchers tested 20 healthy adults, people with prediabetes, and people with type 2 diabetes. The goal was to learn more about how oxygen lev…

This study looked at whether artificial sweeteners like Equal (aspartame) and Splenda (sucralose) raise blood sugar in adults with prediabetes. Fourteen participants ate controlled breakfasts with or without sweeteners, and their glucose levels were tracked for two hours. The goa…

This study looked at whether showing people their real-time blood sugar levels (using a continuous glucose monitor) changes how much they value a milk drink made with mulberry leaf extract. About 170 non-diabetic Chinese adults aged 45-75 took part. The goal was to see if seeing …

This pilot study looked at whether removing oxysterols (harmful compounds in cooked animal foods) from the diet could improve insulin production in African Americans with prediabetes or early type 2 diabetes. Twelve participants ate a plant-based diet free of oxysterols for a per…

This study looked at whether exercising in the morning or afternoon makes a difference for people with type 2 diabetes or prediabetes. Thirty-six adults did supervised exercise sessions at either 7-11am or 4-8pm for up to 10 sessions. Researchers measured changes in body weight, …

This small study looked at whether sodium phenylbutyrate can lower certain amino acids in the blood of obese men with prediabetes. Researchers wanted to see if this change would also improve blood sugar levels and muscle metabolism. Only 8 men participated, so results are very pr…

This study looked at whether two common artificial sweeteners—saccharin and acesulfame-potassium—affect blood sugar levels in middle-aged and older adults with prediabetes. Fourteen participants ate controlled breakfasts with or without these sweeteners, and their blood glucose w…

This study looked at how the hormone glucagon affects the liver's ability to break down proteins and fats in people with obesity, type 2 diabetes, and fatty liver disease. Researchers wanted to understand if the body becomes resistant to glucagon in these conditions. A total of 2…

This small pilot study looked at whether a 5-day fasting-mimicking diet (FMD) is practical for Asian Americans with prediabetes. Thirty participants followed the special low-calorie diet for five days and had their blood sugar and physical measurements checked before and after. T…

This study looked at how prediabetes and type 2 diabetes impact memory, physical abilities, and tiredness in people aged 60 and older. Researchers compared 94 older adults with normal blood sugar, prediabetes, or diabetes using tests of thinking, walking, and fatigue. The goal wa…