PREDIABETES

This study tests whether empagliflozin, a drug used for type 2 diabetes, can improve blood sugar control in adults with prediabetes who are overweight or obese. Sixty participants will receive either the drug or a placebo for 13 weeks. Researchers will measure how the body handle…

This study looks at whether adding CPAP therapy for sleep apnea to standard lifestyle changes can improve blood sugar and blood pressure in people with prediabetes who are overweight. About 174 participants will use CPAP alongside a lifestyle program, and researchers will measure…

This study tests whether portable devices like handheld ultrasound and blood glucose monitors can catch chronic diseases (such as diabetes, high blood pressure, and kidney disease) earlier than standard care. About 200 adults aged 18 to 75 will use these devices at their doctor's…

This study looks at whether routine blood sugar testing during dental exams can identify people with advanced gum disease who also have undiagnosed diabetes or prediabetes. About 300 adults with severe periodontitis will get a finger-prick blood test. The goal is to see how commo…

This study tests a new tool that helps doctors give personalized advice to people with prediabetes. The tool uses a questionnaire to see how ready a person is to make healthy changes, then suggests the best next steps, like a health coach or diabetes prevention program. About 100…

This study tests whether a combination of metformin (a diabetes drug) and a digital lifestyle program can safely prevent diabetes in adult survivors of childhood cancer who have prediabetes. About 96 participants will take part. The goal is to see if this approach is feasible and…

This study looks at whether adding supervised cycling and rowing to a Mediterranean diet helps women with prediabetes control their blood sugar better than diet alone. About 30 women will be split into three groups based on their current blood sugar levels. They will follow the d…

This study looks at whether adding peer support and vouchers for healthy food helps people with prediabetes stick with a diabetes prevention program. About 142 low-income adults will either join the standard program or get extra support and food vouchers. The goal is to see if th…

This study tests whether berberine, a natural compound, can prevent heart disease and diabetes in over 2,000 adults in China who are at high risk. Participants have prediabetes, obesity, and other risk factors. They take berberine or a placebo for a year to see if it improves blo…

This study looks at whether the amount of effort during weightlifting changes blood sugar levels in people with prediabetes or type 2 diabetes. Fifteen adults will try a high-effort workout, a low-effort workout, and a no-exercise day to compare results. Researchers will also che…

This study looks at how eating whole wheat bread affects gut bacteria and health in adults with prediabetes. About 65 participants will eat either whole wheat or white bread for two weeks, then switch. Researchers will measure blood sugar, insulin, and inflammation markers to see…

This study is a review of many smaller trials that looked at what happens when people replace animal protein (like meat, eggs, and dairy) with plant protein (like beans, nuts, and seeds). The goal is to see if this simple swap can improve blood sugar, cholesterol, blood pressure,…

This study aimed to see if adding pramlintide to semaglutide changes appetite and eating habits in obese adults with prediabetes. Researchers planned to give 40 participants weekly semaglutide shots for 24 weeks, then add either pramlintide or a placebo for two more weeks. The go…

This study looks at whether a program of exercise and a dietary supplement called nicotinamide riboside (similar to vitamin B3) can improve muscle health and insulin resistance in adult survivors of childhood cancer who have prediabetes. The study involves 20 participants and foc…

This study looked at over 16,000 adults aged 45-70 with at least one risk factor (like high blood pressure or smoking) but no known heart disease. Researchers used ultrasound and urine tests to find hidden artery thickening and early kidney problems. The goal is to learn what fac…