Exercise and supplement combo tested to fight prediabetes in childhood cancer survivors
NCT ID NCT05023993
First seen Nov 10, 2025 · Last updated Jun 22, 2026 · Updated 28 times
Summary
This pilot study tests whether a home exercise program plus a dietary supplement called nicotinamide riboside (similar to vitamin B3) can improve muscle health and insulin resistance in adult survivors of childhood cancer who have prediabetes. The study includes 20 participants and focuses on whether the program is practical and well-tolerated. If successful, it may lead to larger studies aimed at preventing diabetes in this high-risk group.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nicotinamide riboside (a dietary supplement similar to vitamin B3) and a home exercise program
What this could lead to
If it works, this could point toward a way to help childhood cancer survivors manage prediabetes and improve muscle health.
What could go wrong
This is a very small pilot study (20 people) focused on feasibility, not on proving the treatment works. The results may not apply to everyone, and the supplement or exercise may not show clear benefits.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.