PREDIABETES

This study looks at whether a pharmacist-led program using continuous glucose monitors (CGMs) can help people with prediabetes better control their blood sugar and make healthier choices. About 40 adults aged 18-70 with prediabetes will wear a CGM for 4 weeks and receive pharmaci…

This study tests an investigational drug called MOTS-c in 120 adults with prediabetes and overweight or obesity. Participants will receive either MOTS-c or a placebo for 12 weeks, along with lifestyle advice. The goal is to see if MOTS-c improves how the body uses insulin and low…

This small pilot study tests whether eating Greek bottarga (grey mullet fish roe) daily can improve blood sugar, cholesterol, and inflammation in adults with prediabetes, diabetes, or obesity. About 20 participants will compare bottarga to a dairy product over 8 weeks. The goal i…

This study looks at whether intermittent fasting (eating only during certain hours) can improve how much insulin the body makes. Researchers will compare a 4-week fasting plan to a regular diet in 200 adults with prediabetes or early type 2 diabetes. The goal is to see if this ap…

This study tests whether meal replacements can help low-income adults with obesity, prediabetes, or type 2 diabetes lose weight and lower blood sugar. Twenty participants will follow an intensive nutrition program and be monitored for weight and A1c changes. The goal is to see if…

This study looks at how not having enough food affects the heart health of people with HIV. Researchers will test a program where trained peers and a phone app help participants get better nutrition and manage conditions like prediabetes and diabetes. The goal is to see if this s…

This study looks at whether artificial intelligence (AI) can give personalized toothbrushing and flossing advice as well as a dentist can for people with prediabetes. Prediabetes is a condition where blood sugar is higher than normal but not yet diabetes, and it is linked to gum …

This study is testing whether using a continuous glucose monitor (CGM) can help overweight teens with prediabetes follow lifestyle changes better. The goal is to see if real-time glucose feedback improves insulin sensitivity and reduces diabetes risk. About 15 teens aged 10-17 wi…

This study tests a special drink with carob extract (NUTIFOOD) to see if it helps people with prediabetes control their blood sugar. About 30 adults aged 18-65 with prediabetes will drink either the carob product or a placebo for a period. Researchers will measure blood sugar and…

This study tests whether a mobile app called PortionSize Ed can help adults who recently had a stroke and have prediabetes or type 2 diabetes follow a Mediterranean diet. Forty participants will be split into two groups: one uses the full app with dietitian support, the other use…

This study compares three diets in 175 adults who are overweight or have prediabetes or type 2 diabetes: a keto diet with healthy canola oil, a traditional keto diet high in saturated fat, and a standard low-fat diet. Researchers will measure effects on heart disease risk factors…

This study looks at whether eating peanuts every day can improve blood sugar, blood pressure, memory, and gut health in adults with prediabetes. Researchers will enroll 72 racially diverse men and women aged 20-59. Participants will eat peanuts or avoid them for set periods, and …

This study tests whether connecting youth (ages 12-25) to community programs rooted in Native Hawaiian culture can improve their mental and chronic health. About 100 participants from the Wai'anae area will take part in summer or school-year programs and complete surveys over 8 m…

This 16-week study is testing different combinations of diet and exercise to find the most effective weight loss plan for 30 adults with prediabetes and physical disabilities. Participants start with either a high or low carbohydrate diet, and those who don't lose enough weight a…

This study compares two approaches to prevent type 2 diabetes in 40 adults with prediabetes who are overweight or obese. One group follows the standard Diabetes Prevention Program, while the other adds sleep health advice and time-restricted eating. The goal is to see which metho…

This study tests whether wearing a continuous glucose monitor (CGM) and watching AI-made health videos on a smartphone can help people with prediabetes keep their blood sugar under control. The goal is to stop prediabetes from turning into type 2 diabetes. About 50 adults aged 35…

This study tests whether adding hands-on nutrition demonstrations helps people at risk for prediabetes stick with the Diabetes Prevention Program. About 20 adults in Los Angeles will take part. The goal is to see if this approach is practical and well-liked, not to cure or treat …

This study tests a behavioral program called Regulation of Cues (ROC) for Latinas who have prediabetes and obesity. The goal is to see if the program helps them lose weight and prevent type 2 diabetes. Thirty women aged 18-55 will participate in 14 sessions and report how helpful…

This pilot study tests whether a 12-week, family-centered whole foods diet (without calorie counting) can prevent type 2 diabetes in adults with prediabetes. About 30 adult-child pairs will participate, with half receiving the diet intervention and half continuing usual care. The…

This study tests whether using smart wearable devices (like fitness trackers) along with a mobile health program can improve heart health in overweight or obese adults who have early signs of heart problems, such as slightly high blood pressure or blood sugar. Researchers will tr…

This study looks at whether eating only during certain hours (early or late in the day) can help control blood sugar and improve heart health in people who are overweight or have prediabetes or type 2 diabetes. Researchers will track blood sugar levels and other health markers in…

This study tests whether a cold water extract from saffron flower petals, taken just before a meal, can improve blood sugar and metabolism in 20 adults with obesity or prediabetes. Participants will drink either the extract or plain water before eating white bread, and researcher…

This study tests whether limiting food intake to a 9-hour window each day (time-restricted eating) can improve heart and metabolic health in people with obesity and prediabetes. Researchers will measure insulin sensitivity, blood sugar control, and fat tissue changes over 12 week…

This study looks at how an 8-week exercise program affects metabolism in 40 overweight or obese adults with prediabetes. Researchers will measure changes in body fat, blood sugar, and other health markers, and use advanced cell analysis to understand the molecular changes. The go…

This study looks at how the hormone glucagon affects insulin release and blood sugar levels in people with prediabetes. Researchers will compare what happens when glucagon is given versus when sugar is given. The goal is to better understand how the body controls blood sugar duri…

This study looks at whether walking in nature or walking in built-up areas (like shopping centers) is better for reducing stress and anxiety in adults with prediabetes. About 216 people aged 25-64 with prediabetes will walk 150 minutes per week for six weeks in each environment. …

This study from Stanford University looks at why people's blood sugar levels react differently to the same foods. Using continuous glucose monitors, researchers will track 100 healthy adults, people with prediabetes, and those with type 2 diabetes after eating specific meals. The…

This study looks at how genes influence the body's response to a natural hormone called GLP-1 in Mexican-Americans with prediabetes. Researchers will analyze DNA and gene activity to understand why some people respond differently to GLP-1, which helps lower blood sugar and weight…

This study is looking for early warning signs of pancreas cancer in people at higher risk, such as those with new diabetes, pancreas cysts, or a family history. Researchers will collect blood samples and health data from 1250 adults over time. The goal is to find markers that cou…