Pork vs. plants: which protein helps prediabetes?
NCT ID NCT06025292
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how lean pork loin and plant-based protein affect muscle building and blood sugar control in adults with prediabetes. Twenty participants aged 40-65 will eat prepared meals for three days. Researchers will measure muscle protein synthesis and glucose levels to see if one protein source is better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lean pork loin and plant-based protein
- What this could lead to
- If successful, this could show that lean pork helps maintain muscle and control blood sugar better than plant protein in people with prediabetes.
- What could go wrong
- This is a very small, short-term study (20 people, 3 days of meals). Results may not apply to real-world diets or long-term health.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Sep 2024
- Expected to finish
-
Jan 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1\. Males and females ages 40-65 years. * 2\. BMI 25 to ≤40 kg/m2 (or body fat % ≥25% in males or ≥36% in females) * 3\. Capable of providing informed consent. * 4\. COVID-19 negative and/or asymptomatic. * 5\. Willing to abstain from drinking alcohol or consuming marijuana and CBD products during the 4-day study meal period * 6\. HbA1c: 5.7-6.4% or fasting glucose 100-125 mg/dL Exclusion Criteria: * 1\. Participant who does not/will not eat animal protein sources. * 2\. Allergy to wheat, soy, or common ingredients in plant-based protein products. * 3\. Body mass index \<25 kg/m2 or \>40 kg/m2. * 4\. Hemoglobin \<10g/dL at screening. * 5\. Platelets \<150,000/uL at screening. * 6\. History of chemotherapy or radiation therapy for cancer in the 6 months prior to enrollment. * 7\. History of gastrointestinal bypass/reduction surgery. * 8\. Pregnant or lactating individuals. * 9\. History of a chronic inflammatory disease (e.g. Lupus, Crohn's disease) * 10\. Currently receiving androgen (e.g., testosterone) or anabolic (e.g., GH, IGF-I) therapy. * 11\. Currently using prescription blood thinning medications. * 12\. Currently using corticosteroid medications (cortisone, hydrocortisone, prednisone, etc.). * 13\. Unable or unwilling to suspend aspirin use for 7 days prior to Visit 3 and Visit 7. * 14\. Unwilling to avoid using protein or amino-acid supplements during participation. * 15\. Unwilling to fast overnight. * 16\. Unwilling to avoid alcohol, marijuana and CBD products for the four study days. * 17\. Participants on glucagon-like-peptide-1 receptor agonist (GLP-1-RA) medications for \<1 month or with less than one treatment dose (injection) every two weeks
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Hyperglycaemia (non diabetic) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72205, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can four minutes of hard exercise match a longer workout for blood sugar?
- Can a Plant-Based diet program help patients lose weight and improve heart health?
- Can a health coach in your patient portal help you lose weight?
- Glucose sensor may flag diabetes risk in cystic fibrosis
- Diabetes drug tested to stop prediabetes in its tracks
- Can a 9-Hour eating window reset blood sugar and body rhythms?