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Could diabetes drugs be the key to halting heart disease?

NCT ID NCT07254572

First seen Jan 04, 2026 · Last updated Jun 18, 2026 · Updated 24 times

Summary

This study compares two newer diabetes drugs, semaglutide and dapagliflozin, against the standard drug metformin in 300 people with pre-diabetes and coronary artery disease. The goal is to see which drug best slows or reverses the buildup of plaque in heart arteries over 24 months. Participants will take the medication long-term to manage their condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institute of Cardiology, Department of Coronary Artery and Structural Heart Diseases

    RECRUITING

    Warsaw, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

coronary artery disorder prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.