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Mango a day keeps prediabetes at bay?

NCT ID NCT06159543

Disease control Sponsor: Loma Linda University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether eating 1.5 cups of fresh mango daily for 12 weeks can improve blood sugar, cholesterol, and inflammation in people with prediabetes. Thirty-one participants will eat mango for 12 weeks, then take a break, and then avoid mango for another 12 weeks. Researchers will compare health markers between the two periods to see if mango makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fresh mango
What this could lead to
If it works, this could suggest that adding mango to your diet helps manage prediabetes and related heart risks.
What could go wrong
This is a small, early-stage trial with only 31 participants. Results may not apply to everyone, and the effect might be small or not last.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 31 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * HgbA1c of 5.7 to 6.4% indicative of prediabetes * Abdominal obesity as defined as a waist circumference \>102 cm for men or \>88 cm for women or BMI 25-39 kg/m2 Exclusion Criteria: * Self-reported chronic disease history (diabetes, heart disease, cancer, kidney disease, inflammatory bowel disease, etc.) * Pacemaker * Mango allergies * Latex allergies (cross-reactive with mango) * Smoking, use of tobacco, or high alcohol intake (\>2 drinks/day for men or \>1 drink per day for women) * Recent significant weight loss (\>5% within 6 months of study enrollment) * BMI \>39 kg/m\^2 * Pregnancy or lactation * Use of medication and/or supplements affecting glycemic indicators or lipids * Habitual mango intake of \>3 servings per week and/or habitual fruit intake of \>2 servings per day * Not able to read and/or communicate in English

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Conditions

The condition(s) this trial relates to.

Dyslipidemias hyperglycemia hyperlipidemia Inflammation inflammatory disease inherited lipid metabolism disorder Insulin Resistance prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dyslipidemias Hyperglycemia Inflammation Insulin resistance Oxidative stress

Contacts and locations

Locations

  • Nutrition Research Center, School of Public Health, Loma Linda University

    Loma Linda, California, 92350, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.