Timing your workout: morning or evening for better blood sugar?
NCT ID NCT06292000
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to see if exercising in the morning versus the evening changes how the body handles sugar in adults with prediabetes. Participants would have completed short bouts of morning exercise, evening exercise, and no exercise, with their blood sugar and insulin levels measured closely. The study was withdrawn before enrolling anyone, so no results are available.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Started
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Feb 2024
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 20-40 years. * Biologically female participants with regular menstruation * Body mass index (BMI) ≥ 30.0 to ≤ 40.0 kg/m2 * Prediabetes as defined by the American Diabetes Association (HgbA1c ≥ 5.7% to \< 6.5% or fasting glucose ≥ 100 to \< 126 mg/dL) * Physically inactive (\< 100 min/wk of regular exercise) * No contraindications to exercise or limitations on ability to be physically active * Weight stable (weight change \< 5kg in past 3 months) * Not currently pregnant or lactating, not pregnant within the past 6 months or planning to become pregnant in the next 6 months. Exclusion Criteria: * History or symptoms suggestive of cardiovascular disease or congestive heart failure * Diastolic blood pressure \> 100 mmHg, systolic blood pressure \> 160 mmHg, or resting heart rate \> 100 bpm * History of type 1 or type 2 DM (or fasting glucose ≥126 mg/dL or Hemoglobin A1C ≥6.5% on screening labs) * Current use of medications that effect SI (oral steroids, metformin, GLP1 receptor agonists, etc). * Chronic kidney disease (CKD, stage 4 or higher) * TSH, electrolytes, hematocrit, white blood cell count, or platelets significantly outside the normal reference range on screening labs * Triglycerides \> 400 or LDL \> 200 on screening labs * Clinically significant abnormality on resting ECG, presence, or history of any other metabolic or chronic health problems which would affect appetite, food intake, energy metabolism, or ability to participate in exercise, * History of obstructive sleep apnea, primary insomnia, night-time shiftwork, rotating work, or other atypical sleep patterns. * Current or recent (within 1 month) zero or very low carbohydrate diet (\< 10% daily calories from carbohydrates).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Colorado
Aurora, Colorado, 80045, United States
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