Can a very Low-Carb diet beat standard advice for prediabetes?
NCT ID NCT05235425
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 35 times
Summary
This completed study compared two versions of the Diabetes Prevention Program in 304 overweight adults with prediabetes. One group followed the standard lower-calorie, lower-fat diet, while the other tried a very low-carbohydrate diet. Researchers measured changes in blood sugar control (HbA1c), weight, and inflammation over 12 months to see which approach works better for preventing type 2 diabetes.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Michigan
Ann Arbor, Michigan, 48109, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
very low-carbohydrate diet
What this could lead to
If successful, this could point toward a more effective dietary approach for preventing type 2 diabetes in people with prediabetes.
What could go wrong
This is a completed study, but results are not yet widely reported. The low-carb diet may be harder to stick with long-term, and individual results can vary.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.