Can a very Low-Carb diet beat standard advice for prediabetes?

NCT ID NCT05235425

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed study compared two versions of the Diabetes Prevention Program in 304 overweight adults with prediabetes. One group followed the standard lower-calorie, lower-fat diet, while the other tried a very low-carbohydrate diet. Researchers measured changes in blood sugar control (HbA1c), weight, and inflammation over 12 months to see which approach works better for preventing type 2 diabetes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
very low-carbohydrate diet
What this could lead to
If successful, this could point toward a more effective dietary approach for preventing type 2 diabetes in people with prediabetes.
What could go wrong
This is a completed study, but results are not yet widely reported. The low-carb diet may be harder to stick with long-term, and individual results can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

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Other studies related to the condition(s) this trial covers.