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Gut bacteria and herbal compound show promise for prediabetes in obesity

NCT ID NCT05720299

First seen Jan 06, 2026 · Last updated Jun 18, 2026 · Updated 25 times

Summary

This study looked at whether a gut bacterium called Akkermansia muciniphila and a natural compound called berberine can help manage prediabetes in obese adults. 110 overweight or obese people with prediabetes were given either the bacterium, berberine, or a placebo for 12 weeks. The goal was to see changes in blood sugar, weight, and other health markers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The Seventh Affiliated Hospital of Southern Medical University

    Foshan, Guangdong, 514500, China

Conditions

The condition(s) this trial relates to.

Obesity prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.