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Scientists probe Glucagon's role in liver health and diabetes

NCT ID NCT05500586

First seen Nov 10, 2025 · Last updated Jun 16, 2026 · Updated 33 times

Summary

This study looked at how the hormone glucagon affects the liver's ability to break down proteins and fats in people with obesity, type 2 diabetes, and fatty liver disease. Researchers wanted to understand if the body becomes resistant to glucagon in these conditions. A total of 21 participants completed the study, which involved measuring amino acid clearance with and without glucagon.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

The condition(s) this trial relates to.

fatty liver disease Insulin Resistance metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder prediabetes syndrome type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.