Timing your meals may ward off diabetes, study finds
NCT ID NCT03504683
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether limiting when you eat (time-restricted eating) can improve blood sugar control and heart health in adults with prediabetes. 108 participants were assigned to eat only between 8am-3pm, 1pm-8pm, or a normal 12-hour eating window for 8 weeks. All meals were provided. The goal was to see if changing meal timing alone, without changing what you eat, can help prevent type 2 diabetes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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108 people
The number who actually took part.
- Started
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Aug 2020
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 30-70 years old * Prediabetic as determined by HbA1c between 5.7-6.4% or fasting glucose between 100-125 mg/dl with HbA1c \>= 5.1% * Fasting insulin less than 100.0 mU/l and, if HbA1c \<5.7%, must also have fasting insulin \>= 8.0 mU/l * BMI between 30-60 kg/m\^2 * Wake up at a regular time between 5-8 am Exclusion Criteria: * Been diagnosed with diabetes or on diabetes medication or any medication known to affect glucose or 24-hour rhythms in blood pressure * On weight loss medication * Change in the dosage of a chronic medication within the past 2 months * Have a clinically significant laboratory abnormality (e.g., abnormal hemoglobin levels) * Significant gastrointestinal disease, major gastrointestinal surgery, or gallstones * Significant cardiovascular, renal, cardiac, liver, lung, adrenal, or nervous system disease that might compromise the participant's safety or data validity * Evidence of cancer (other than non-melanoma skin cancer) within the last 5 years * Pregnant or breastfeeding * Diagnosed psychiatric conditions * Sleep disorder, circadian disorder, or regularly sleep less than 6 hours per night * Major change in health or medical history in the past 3 months * Currently perform overnight shift work * Regularly eat within a \<10.5-hour period each day * Lost or gained more than 4% of weight in the past 2 months * Traveled more than 2 time zones away in the 2 months prior to enrolling in this study * Will travel outside the Central time zone in the 2 weeks prior to testing * Will travel more than 1 time zone away during this study * Behavioral factors or other circumstances that may make it difficult for you to follow the study requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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Other studies related to the condition(s) this trial covers.
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