DIABETES MELLITUS

This study tested whether a continuous glucose monitor (CGM) that alerts nurses to high or low blood sugar can help surgical patients with diabetes stay in a healthy glucose range. About 200 adults with diabetes who had surgery wore the Dexcom G7 device for up to 10 days. The goa…

This study looked at whether alerts from continuous glucose monitors (CGMs) help improve blood sugar control in adults with type 1 or 2 diabetes who need intensive insulin therapy while in the hospital. Over 500 participants were randomly assigned to use CGM with alerts or withou…

This study tested a medicine called tirzepatide in children and teenagers (ages 10 to under 18) with type 2 diabetes that was not well controlled by metformin or insulin. The goal was to see if tirzepatide could safely lower blood sugar levels better than a placebo. The study las…

This study tested the safety and effectiveness of the Omnipod 5 SmartAdjust 2.0 system, an automated insulin pump, in 48 people aged 2 to 70 with type 1 or type 2 diabetes. The system uses a continuous glucose monitor to automatically adjust insulin delivery. The main goals were …

This study tested a new way to help older adults with type 2 diabetes manage their blood sugar. Instead of traditional finger-prick tests, participants used a non-invasive device and a health app to get personalized care. 60 people aged 60 and older took part in the 8-week trial …

This study tested whether adding a community health worker to the care team helps children with type 1 diabetes improve blood sugar control and reduce hospital visits. 84 children with type 1 diabetes for over a year and with recent high blood sugar or hospital visits took part. …

This study looked at 600 hospitalized patients with diabetes who were not in the ICU. It compared two blood sugar targets: a tight target (130 mg/dL or lower) versus a standard target (130-180 mg/dL). The goal was to see which approach better prevents serious complications like d…

This study tested whether taking high doses of omega-3 fatty acids (fish oil) and vitamin D together is safe and might help people with type 1 diabetes keep making some of their own insulin. It included 27 people aged 6 to 65, both newly diagnosed and those living with diabetes f…

This study looked at whether adding vitamin B12 to the usual diabetes medicine dapagliflozin could improve blood sugar levels in 80 adults with type 2 diabetes. Participants took either vitamin B12 or a placebo alongside their regular treatment. The main goal was to see changes i…

This study tested a special nutritional drink (Nutren Diabetes) designed for people with diabetes who have trouble swallowing. Researchers compared it to another diabetes drink to see if it controlled blood sugar just as well over 24 hours. A total of 233 adults with diabetes too…

This study looked at 100 people with diabetes who had a liver transplant. It compared two diabetes drugs, dapagliflozin and sitagliptin, to see which one better reduces fat buildup in the liver and improves body composition over 12 months. Participants continued their usual medic…

This study tested two antibiotic gels (metronidazole and minocycline) against gum disease in 380 adults with diabetes. Participants received deep cleaning alone or with one or both gels. Researchers measured gum pocket depth, color, and bleeding at 7 and 15 days to see which trea…

This early-phase study tested whether a new cell therapy is safe for people with type 1 diabetes. Researchers took immune cells from 32 participants, turned them into 'tolerogenic dendritic cells' in a lab, and gave them back to the patients. The goal was to see if these cells co…

This early-phase study tested whether infusions of donor stem cells could help repair damaged blood vessels in 26 adults with type 2 diabetes and symptomatic heart disease. The goal was to see if the cells could improve the body's natural repair system and blood vessel function. …

This study looked at whether weight-loss surgery (vertical sleeve gastrectomy) can improve diabetes and kidney health in teens aged 12-21 with type 2 diabetes. Researchers measured how well the pancreas and kidneys worked before and after surgery. The goal was to see if surgery c…

This study tested whether a virtual weight management program combined with a continuous glucose monitor could help adults with type 2 diabetes lower their blood sugar levels. 152 overweight or obese adults with type 2 diabetes participated. The program was delivered through a di…

This study tested a program to help people with high blood pressure and diabetes in Brazil get better control of their conditions. Over 5,800 adults from 35 health centers took part. The program included telehealth tools, text messages, and extra training for healthcare workers. …

This study tested a new device used during an endoscopy to regenerate the lining of the first part of the small intestine in people with type 2 diabetes. The goal was to see if the procedure is safe and could help improve blood sugar control. Twenty adults with diabetes not well …

This study tested a new way to help people with two or more long-term health problems like HIV, high blood pressure, diabetes, asthma, or depression. Over 1,800 adults aged 40 and older in South Africa took part. Some clinics used a special decision-support tool and home visits f…

This study looked at whether Baduanjin, a gentle form of exercise, can help people with type 2 diabetes. 42 adults aged 50-60 with diabetes for 5-10 years took part. The goal was to see if the exercise could lower stress hormones and blood sugar, and improve quality of life. Whil…

This pilot study tested whether helping people with diabetes manage their medical costs and connecting them with a peer supporter could improve their blood sugar and blood pressure. 61 adults with diabetes who had trouble affording their care took part. Some received only financi…

This study looked at 40 people with diabetes and a high risk of bleeding who received a special heart stent. Researchers used a camera inside the artery to check if it healed enough after one month. If it did, patients stopped one of their two blood thinners early. The goal was t…

This study tested a telenursing program where nurses provided health education and lifestyle advice over the phone to 70 adults with type 2 diabetes in Bangladesh. The goal was to help patients better manage their diet, exercise, and medication to improve blood sugar control. Par…

This study looked at whether taking aspirin twice a day (100 mg each time) works better than the usual once-a-day dose to prevent another heart attack, stroke, or urgent heart procedure in people with diabetes who have had a recent heart attack or unstable angina. About 2,500 par…

This study tested a telecare program where diabetes patients had video consultations with healthcare providers instead of in-person visits. The goal was to see if this approach could help manage blood sugar levels effectively. The study involved 780 adults with diabetes and measu…

This pilot study tested whether using smart insulin pens together with continuous glucose monitors (CGMs) can help people with type 2 diabetes better control their blood sugar. Thirty adults with poorly controlled diabetes took part. The goal was to see if this technology could l…

This study tested a mobile app called Mobile Diabetes Detective (MoDD) to see if it helps people with type 2 diabetes better manage their condition. 248 adults used the app to improve problem-solving skills and self-care. The goal was to lower blood sugar levels and improve overa…

This pilot study tested whether people with type 2 diabetes and early kidney disease can take part in a clinical trial from home. Twelve participants collected their own urine, blood, and blood pressure readings remotely. They took empagliflozin first, and based on their response…

This early-phase study tested whether transplanting insulin-making cells (islets) into people with type 1 diabetes who already had a kidney transplant could help them stop using insulin. Only 3 participants were enrolled, and they stayed on lifelong anti-rejection drugs. The goal…

This study looked at whether giving diabetes patients who are at risk for food insecurity money to buy fruits and vegetables, along with nutrition education, could improve their blood sugar control and reduce emergency room visits. Over 2,000 adults participated, with some receiv…

This study tested whether babies with a rare, permanent form of diabetes caused by specific gene changes could safely switch from daily insulin injections to an oral diabetes pill called glibenclamide. Nineteen infants and children took part. Researchers monitored their blood sug…

This study looked at whether a fiber-enriched, low-sodium liquid food could help control blood sugar and blood pressure in long-term care residents with diabetes who are fed through a tube. 32 adults received the special formula as their only food for 3 months. Researchers measur…

This study tested a program where community health workers helped young adults (ages 18-35) from underrepresented minority groups with type 1 diabetes start and continue using diabetes technology like continuous glucose monitors and insulin pumps. Over 9 months, 119 participants …

This study tested a virtual health program for African immigrants aged 25-75 who are uninsured and have at least two risk factors like high blood pressure, prediabetes, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over six month…

This study tested how well the True Vie I3 continuous glucose monitor (CGM) measures blood sugar levels in 159 adults with type 1 or type 2 diabetes. Participants wore the device while researchers compared its readings to standard lab measurements. The goal was to see if the moni…

This study looked at whether measuring ferritin (a protein that stores iron) in early pregnancy can help predict which women will develop gestational diabetes later. Researchers followed 556 pregnant women, checking their ferritin and other iron markers early on. The goal was to …

This study looked at whether foot-ankle exercises or walking exercises can help people with type 2 diabetes who have foot nerve problems. 375 adults with diabetes did either foot exercises, walking, or received standard care for 12 weeks. Researchers measured foot sensation, stre…

This study tested a special educational tool for parents of children under 6 with type 1 diabetes. The goal was to see if the tool helps improve blood sugar control and prevent dangerous events like low blood sugar or ketosis. The study included 24 children and followed them for …

This study tested a new method called inforatio to help heal diabetic foot ulcers. The technique involves making small cuts in the wound to trigger the body's natural healing response. 100 adults with diabetes took part. The main goal was to see if the ulcers healed completely.

This study looked at whether a program called COPE helps Navajo people with diabetes and other chronic conditions. The program trains community health workers to support patients and coordinate with doctors. Researchers compared health measures like blood sugar and blood pressure…

This small pilot study tested whether offering financial rewards for exercise and healthy food could help people with obesity or diabetes. Eight participants from a low-income community were split into two groups to see if incentives increased walking and improved weight. The mai…

This study tested a new way to help staff at mental health programs provide better care for heart health risks like diabetes, high blood pressure, and high cholesterol. 85 staff and people with serious mental illness took part. The goal was to see if the program improved how staf…

This study looked at how the amount of salt in the diet changes the way the diabetes drug ertugliflozin works on blood pressure and kidneys. Overweight adults with type 2 diabetes followed either a low-salt or high-salt diet while taking the drug or a placebo. The goal was to und…

This study tested five different blood glucose monitors in 501 adults with type 1 or type 2 diabetes who use insulin. The goal was to see how well each device measures blood sugar levels. Participants used multiple devices to compare accuracy and ease of use.

This study tested a special type of scan (SPECT/CT) to measure blood flow in leg muscles. Researchers compared healthy people to those with peripheral artery disease (PAD) and diabetes. They also used the scan to see if blood flow improved after a procedure to open blocked leg ar…

This study looked at two methods for assigning care coordinators to older adults (65+) who have heart disease or related risks like diabetes or high blood pressure. The goal was to see which method better prevents emergency room visits and hospital stays. Researchers compared ass…

This pilot study tested whether a new program to prevent low blood sugar (hypoglycemia) is practical and well-liked by patients, doctors, and clinic staff. It involved 35 adults with diabetes who take medications that can cause low blood sugar. The goal was to gather feedback and…

This study explored how malnutrition, diabetes, and worm infections influence the body's response to latent tuberculosis (LTBI) in a South Indian population. Researchers enrolled 626 people aged 14 to 65, with or without LTBI, and measured these risk factors along with immune bio…

This study checked whether acetaminophen (Tylenol) interferes with the Biolinq continuous glucose monitor, a device that measures blood sugar through the skin. Thirty-one adults with diabetes wore the Biolinq sensor and a standard monitor for three days. On the third day, they to…

This study tested a new wearable sensor (Biolinq) that measures blood sugar continuously for up to 5 days in 247 adults with diabetes. Participants wore the sensor and a standard monitor, and compared readings with lab tests. The goal was to see if the new sensor is safe and accu…

This study tested whether a mobile app helps people aged 70 and older with diabetes manage their blood sugar and daily life. Sixty participants were split into two groups: one used the app, the other did not. Researchers measured blood sugar control, physical function, and qualit…

This study looked at whether viral infections in pregnant women with diabetes might increase the chance of their babies being born with heart defects. Researchers analyzed blood and stool samples from 114 women to detect viruses and immune responses. The goal was to gather initia…

This study looked at whether adults with type 2 diabetes in Cameroon are more likely to get malaria and other parasitic infections. Researchers followed 406 people with and without diabetes for one year, testing blood and stool samples. The goal was to understand how diabetes and…

This study tested whether regular meetings between different types of doctors could work well in a hospital to help patients who have diabetes along with other long-term health problems. About 55 adults with diabetes and at least one other condition (like heart, kidney, or lung d…

This study tested whether continuous glucose monitors (CGMs) can help track blood sugar levels in hospitalized adults with diabetes. 40 patients wore a CGM device during their hospital stay to see how well it detected low and high blood sugar events. The goal was to gather eviden…

This study followed 201 adults with diabetes who were hospitalized for COVID-19 in Algeria. Researchers tracked their blood sugar control, weight, and kidney function for up to one year after leaving the hospital. The goal was to learn how COVID-19 affects diabetes management lon…

This study looked at 32 adults aged 40-65 with early-stage diabetic foot to see how pressure on the soles of their feet relates to their ability to stand and balance. Researchers used special pressure mats and balance boards to measure these factors. The goal is to find patterns …

This study examined stool samples from 200 heart attack patients, some with high blood sugar and some without, to see if gut bacteria differ between the groups. Researchers tracked deaths over 12 months to explore whether changes in gut bacteria relate to recovery. The goal was t…

This study looked at why older adults with type 2 diabetes or who are hospitalized lose muscle size, strength, and function faster. Researchers measured leg muscle mass and knee strength in 95 participants. The goal was to find new targets for treatments to slow down muscle loss …

This study followed 99 people who had both an operable pancreatic tumor and diabetes for one year after surgery. Researchers tracked their fatigue, blood sugar control, diabetes self-care, and quality of life to see how these factors change over time. The goal was to better under…

This study compared how much food or liquid remains in the stomach after a standard fasting period in people with and without diabetes. Researchers used ultrasound to measure stomach volume in 592 adults scheduled for elective surgery. The goal was to see if diabetes affects stom…

This study followed 1290 adults with type 1 or type 2 diabetes for two years to see how mental health issues like depression, anxiety, and eating problems relate to blood sugar control. Participants completed surveys, interviews, and daily smartphone check-ins about mood and stre…

This study tested a computer tool that helps doctors identify social needs—like trouble getting food or housing—in African American patients with chronic diseases such as diabetes or high blood pressure. The tool gave doctors a risk score and suggested referrals to community orga…

This study analyzed health records from nearly 1 million Canadian adults to see how the COVID-19 pandemic affected primary care for chronic conditions like diabetes, heart failure, and depression. Researchers looked at changes in doctor visits, tests, and treatments before and du…

This study looked at how diabetes-related physical symptoms impact balance in 58 adults with diabetes. Participants completed a fast stepping test to measure dynamic balance. The goal was to identify which symptoms most affect balance, helping guide future care.

This study looked at the bacteria living in the small intestine and colon of 90 adults, including lean individuals, people with obesity, and those with both obesity and type 2 diabetes. Researchers collected samples during routine endoscopy or colonoscopy to compare gut bacteria …

This study tested strategies to help community health centers routinely ask patients with or at risk for diabetes about social needs like food, housing, and transportation. The goal was to see if using electronic health record tools could increase how often these needs are docume…

This study looked at whether the Dexcom G7 continuous glucose monitor gives accurate readings in diabetes patients who have poor blood circulation during hospital stays. Sixty adults with diabetes wore the device for up to 10 days while receiving standard care. Researchers compar…

This study looked at how the body handles HRS-7535, a potential diabetes drug, in people with mild or moderate liver impairment compared to those with normal liver function. 24 adults participated to measure drug levels and safety. The goal is to understand if liver problems chan…

This study looked at whether certain substances in the blood (endocan, alarin, and galanin-like peptide) are linked to the severity of diabetic retinopathy, an eye problem caused by diabetes. Researchers measured these markers in 90 adults with and without diabetic eye damage and…

This study looked at 542 adults to see if having more fat in the legs lowers the risk of type 2 diabetes, and whether belly fat explains that link. Researchers used body scans and statistical models to understand how fat distribution affects diabetes risk differently for men and …

This study looked at whether a new DNA-based test can better identify bacteria in diabetic foot ulcers compared to standard methods. Researchers enrolled 44 adults with diabetes and an infected foot ulcer. The goal was to see if this test could help doctors choose the right antib…

This study looked at two strategies to improve diabetes care: giving doctors feedback on their performance (profiling) and having a diabetes nurse coordinate care. It included 1891 older adults with diabetes in Texas. The goal was to see if these approaches helped patients meet b…

This study looked at whether web-based birth preparation classes help pregnant women feel more attached to their unborn baby and less scared of giving birth. 120 pregnant women in Turkey took part. The results measured their feelings using questionnaires. The goal was to see if o…

This study looked at whether inflammation is linked to heart disease and diabetes. Researchers compared 150 adults with these conditions to healthy volunteers using blood tests, heart scans, and tissue samples. The goal was to better understand the relationship, not to test a new…

This study tested a computer tool that helps doctors in primary care correctly identify the type of diabetes in adults diagnosed before age 50. The tool uses existing patient data to flag possible misclassification. Researchers interviewed 21 patients and staff to see if the tool…