Early pregnancy iron levels may flag diabetes risk
NCT ID NCT07433465
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether measuring ferritin (a marker of iron stores) in early pregnancy can help predict which women will later develop gestational diabetes. Researchers followed 556 pregnant women, measuring their ferritin and other blood markers early on. The goal was to see if high ferritin levels could identify high-risk women before diabetes develops, potentially allowing for earlier care and better outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test early in pregnancy to identify women at risk for gestational diabetes, allowing for earlier monitoring and lifestyle changes.
- What could go wrong
- This is an observational study, not a treatment trial. The findings need to be confirmed in larger, more diverse groups before any test is widely used. High ferritin may not be the only factor involved.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
-
556 people
The number who actually took part.
- Started
-
Dec 2022
- Finished
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Oct 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Pregnant women at the time of their initial pregnancy diagnosis, typically presenting at prenatal or outpatient clinics.
- Ages
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21 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed pregnancy at an early gestational age. * Provision of clinical and family history (e.g., age, BMI, history of GDM). Exclusion Criteria: * Pre-existing Type 1 or Type 2 Diabetes Mellitus. * Conditions known to significantly alter iron metabolism independent of pregnancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Benha University
Banhā, Al Qalyoubia, 13511, Egypt
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