DIABETES MELLITUS

This study looks at whether using a real-time continuous glucose monitor (CGM) can help people with type 2 diabetes and worsening heart failure better manage their blood sugar. About 140 adults admitted to the hospital for heart failure will be monitored during their stay and for…

This study looks at whether eating proteins and vegetables before carbohydrates (meal sequencing) can improve blood sugar control in 70 adults with diabetes or prediabetes who also experience food insecurity. Participants will receive free produce boxes and either standard nutrit…

This study tests a comprehensive management service package for older adults (65+) who have two or more chronic conditions like high blood pressure, diabetes, or arthritis. The program includes digital tools, personalized guidance, and ongoing support. Researchers will compare it…

This study tests a new gel called GM-XANTHO for treating stage 2 or 3 pressure ulcers (bedsores) in adults, including those with diabetes. About 58 participants will receive either a low or high dose of the gel plus standard care, or a placebo plus standard care. The goal is to s…

This trial tests if islet cells made from stem cells can safely help people with diabetes. About 30 adults who have had diabetes for over 5 years and use insulin will receive an infusion of these cells. The goal is to see if the cells can improve blood sugar control and reduce th…

This study tests a program called Primary Care Connect (PC2) for cancer survivors who also have heart-related conditions like high blood pressure, diabetes, or high cholesterol. The goal is to see if the program helps them stay connected to their primary care doctor and better ma…

This study tests a community-based exercise program for adults aged 50 and older who have at least two chronic conditions, such as heart disease, diabetes, or arthritis. The goal is to see if personalized exercise can improve heart and muscle fitness, mobility, and overall well-b…

This study tests whether using artificial intelligence to screen for diabetic eye disease during regular primary care visits helps more people get the follow-up eye care they need. About 4,000 adults with diabetes who haven't had an eye exam in the past year will take part. The g…

This study checks if a cheap thermal camera (about 200 euros) works as well as a professional one for finding foot hot spots in people with diabetes. Hot spots can signal early foot problems. 130 adults with diabetes will have both cameras take pictures of their feet. The goal is…

This study tests whether a quick, non-invasive facial scan using a smartphone can accurately estimate blood sugar and HbA1c levels. Researchers will compare the scan results with standard lab blood tests in 300 adults in Jakarta, both with and without diabetes. If successful, thi…

This study aims to see if a single-lead electrocardiogram (ECG) analyzed by machine learning can screen for heart conditions, diabetes, and chronic kidney disease. Researchers will enroll about 5000 adults who have already had a full medical exam. They will record a 1-minute ECG …

This study compares several non-invasive methods to measure the hardness of foot calluses in healthy people and those with diabetes. Researchers will use pressure plates, a hardness meter, ultrasound, and infrared cameras during a single session. The goal is to find the most reli…

This study tests whether an oral supplement called DLBS1033 can improve nerve damage symptoms in adults with type 2 diabetes. Over 28 days, 34 participants will receive either the supplement plus standard care or standard care alone. Researchers will measure changes in nerve func…

This study looks at whether having a root canal done in one visit causes less pain afterward than spreading it over multiple visits, specifically for people with diabetes. About 200 diabetic patients needing root canal on a single-rooted tooth will be randomly assigned to one of …

This study tests whether acupressure (a gentle pressure technique) can lower blood sugar and reduce anxiety in people aged 65 and older with diabetes. About 48 participants will be randomly assigned to receive acupressure or a sham procedure. Researchers will measure fasting and …

This study tests whether laser acupuncture can improve arterial stiffness in people with cardiorenal metabolic syndrome (CRMS), a condition linking heart, kidney, and metabolic problems. 35 adults with at least two related conditions (like high blood pressure, diabetes, or chroni…

This study looks at whether changing how health information is presented can help diabetic patients at high risk for foot ulcers better understand their risk. Researchers will compare two types of messages—one focusing on the benefits of good foot care and another on the dangers …

This study looks at how well the mouth heals after a gum graft in people with and without diabetes. Researchers will measure wound size and healing over 90 days in 40 adults. The goal is to understand what factors, like germs and inflammation, affect recovery.

This study looks at how to help VA medical centers better serve women Veterans, especially those in midlife. Researchers will test two different strategies to get more women involved in programs for heart health, weight management, and stress. The study involves 18 VA sites and f…

This study tests a new tool that helps doctors and cancer survivors decide together on the best heart-protecting medications and heart scans. About 60 adult cancer survivors who have not yet seen a heart specialist will take part. The goal is to see if the tool is easy to use and…

This large observational study will follow 100,000 elderly Chinese adults to see how conditions like diabetes, high blood pressure, and high cholesterol impact kidney disease and overall health. Participants will provide blood and urine samples and be tracked over time through cl…

This early-stage study tests a new diabetes medicine called AD-123 in 50 healthy adults. Researchers want to see how safe it is and how the body processes it compared to taking its two components separately. The study does not involve treating diabetes directly.

This study follows 500 Beijing residents aged 60 and older to see how urinary function (like bladder and kidney health) relates to multiple chronic conditions such as diabetes, heart disease, and metabolic syndrome. Participants will have regular health checks, blood and urine te…

This study will observe 100 adults with diabetes and foot ulcers to identify non-vascular risk factors—like infection, poor blood sugar control, and smoking—that make ulcers worse or slow healing. Researchers will track ulcer size and recurrence over one year. The goal is to bett…

This study looks at how well a special type of tooth filling (Giomer) works in people with diabetes compared to those without. Researchers will check the fillings over 18 months to see if they stay in place and prevent new decay. The goal is to understand if diabetes affects how …

This study looks at how well the gums heal after a common gum surgery in people with and without diabetes. Researchers want to see if diabetes slows healing or changes the outcome. About 40 adults will take part and be followed for 6 months after treatment.

This study explores whether advanced eye and brain imaging can help diagnose and treat nerve and blood vessel damage caused by diabetes. Researchers will test a Chinese herbal medicine called Tangshen'an Granule in 160 adults aged 18-70 with diabetes. The goal is to see if the im…

This study watches 46 adults having foot or ankle surgery to see if diabetes changes how fast an ankle numbing shot works and how much pain medicine they need afterward. Researchers will compare diabetic and non-diabetic patients. The goal is to learn more, not to test a new trea…

This study looks at how fear of low blood sugar (hypoglycemia) influences whether people with diabetes stick to their diet and medications. Researchers will survey 100 adults aged 18-65 who have had at least one low blood sugar episode. The goal is to understand this fear better …

This study will use ultrasound to measure stomach volume in 220 adults (with and without diabetes) before elective surgery. The goal is to see if standard fasting guidelines (no food for 6-8 hours, no clear liquids for 2 hours) are enough for diabetic patients, who may have slowe…

This study looks at whether a custom toe divider can help people with diabetes who have had a small toe amputated. Researchers want to see if it improves walking and reduces the risk of new foot sores. The study is small and aims to find out if a larger trial is possible. Partici…

This early-stage study looks at how the body processes HRS9531, a drug for diabetes and weight loss, in people with mild or moderate liver issues compared to those with healthy livers. About 24 adults will receive a single dose to measure drug levels and check for side effects. T…

This study tests a program called SPARK-CGM that helps primary care doctors learn about and prescribe continuous glucose monitors (CGMs) for people with diabetes. CGMs track blood sugar in real-time, helping patients avoid dangerous lows and improve their quality of life. The stu…