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Does feeling stigmatized worsen life quality for men with low testosterone?

NCT ID NCT07752511

Knowledge-focused Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study looks at how anticipated stigma and illness identity affect quality of life in men with hypogonadism (low testosterone). It compares these men to those with other chronic endocrine conditions like diabetes, hypothyroidism, or hypertension. The goal is to see if these psychological factors predict worse quality of life specifically in the hypogonadism group. Participants will complete questionnaires measuring stigma, illness perception, symptoms, and anxiety/depression.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study succeeds, it could highlight how stigma and self-perception affect quality of life in men with hypogonadism, potentially guiding better psychological support and patient-centered care.
What could go wrong
This is an observational study with a relatively small sample size, so findings may not apply broadly. It does not test any treatment, so it cannot directly improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Male patients aged 18 years and older who are routinely followed up at the endocrinology outpatient clinic of Malatya Training and Research Hospital. The population comprises two distinct subgroups: men with a biochemically confirmed diagnosis of hypogonadism and age-matched men diagnosed with other chronic endocrine or metabolic conditions (diabetes mellitus, hypertension, or hypothyroidism) without hypogonadism.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Cases: * Male, aged 18 years or older. * Biochemically confirmed hypogonadism (total testosterone \< 300 ng/dL with at least one clinical symptom). * Regular follow-up at the endocrinology outpatient clinic. * Fluent in reading and understanding Turkish. * Signed informed consent. Controls: * Male, aged 18 years or older. * Diagnosed with diabetes, hypertension, or hypothyroidism under regular endocrinology follow-up. * Total testosterone ≥ 300 ng/dL. * Age-matched to a participant in the case group (±5 years). * Fluent in reading and understanding Turkish. * Signed informed consent. Exclusion Criteria: * Active psychiatric diagnosis (e.g., active psychosis, bipolar disorder). * Chronic inflammatory or rheumatological diseases affecting body composition (e.g., chronic kidney disease, IBD, rheumatoid arthritis, SLE, ankylosing spondylitis). * Uncontrolled co-existing endocrine conditions or severe complications (e.g., HbA1c \> 8.0%, diabetic neuropathy/nephropathy/retinopathy, non-euthyroid state). * Cognitive impairment or dementia precluding questionnaire completion. * Klinefelter syndrome. * Literacy limitations preventing completion of self-report measures. * Additional control exclusion: Diagnosis or clinical suspicion of hypogonadism.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus endocrine system disorder eunuchism hypertensive disorder hypogonadism hypogonadism, male hypothyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endocrine disease Hypertension Hypogonadism, male

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bingöl University Faculty of Physical Therapy and Rehabilitation

    Bingoel, Turkey (Türkiye)

  • Malatya Training and Research Hospital

    Malatya, Turkey (Türkiye)

More trials for these conditions

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