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Gum disease showdown: which antibiotic gel works best for diabetics?

NCT ID NCT06027151

Disease control Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two antibiotic gels (metronidazole and minocycline) in 380 adults with both diabetes and gum disease. Participants received deep cleaning alone or with one or both gels. Researchers checked gum pocket depth and gum color/texture at 7 and 15 days to see which treatment improved gum health most.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

380 people

The number who actually took part.

Started

Oct 2022

Finished

Jul 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Previously diagnosed diabetic patients on either hypoglycemics or insulin therapy suffering from periodontitis Exclusion Criteria: Pregnant or nursing mothers Patients with gestational diabetes Alcoholics Patients under any anti-inflammatory or antibiotic drugs (daily for ˃7 consecutive days) within the last two months of elimination before entering the study. Known allergy to minocycline, or metronidazole. Periodontal surgeries in the past Smoking

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Conditions

The condition(s) this trial relates to.

chronic periodontitis diabetes mellitus periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes mellitus Periodontitis

Contacts and locations

Locations

  • Islamic International Medical Collège, IIMC

    Rawalpindi, Punjab Province, 44000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.