ATRIAL FIBRILLATION

This study tested whether sending mild electrical signals just under the skin could improve symptoms of atrial fibrillation (AF) by controlling heart rate. 46 adults with symptomatic paroxysmal AF who did not respond to standard treatments participated. The approach aims to reduc…

This study tested a new system that uses pulsed energy to fix faulty electrical signals in the heart, aiming to stop episodes of atrial fibrillation (an irregular heartbeat). 392 adults with symptomatic AF that didn't improve with medication took part. The approach focuses on con…

This study looked at 1,284 people with atrial fibrillation who had a successful heart ablation procedure. It compared taking standard blood thinners versus aspirin to prevent strokes. The goal was to see which approach better reduces stroke risk without causing major bleeding.

This study tested two new devices that use pulsed field energy to treat persistent atrial fibrillation (a type of irregular heartbeat). 89 adults who had not responded to medication received a minimally invasive heart procedure. The goal was to see if the devices are safe and can…

This study looked at whether Vidaza, a drug used for acute leukemia, could also help treat atrial fibrillation (an irregular heartbeat). The idea was that Vidaza might reverse harmful DNA changes in heart cells, reducing scarring and improving heart rhythm. Only one person took p…

This study tested a procedure to close a small pouch in the heart (left atrial appendage) in people with atrial fibrillation who are at high risk for both stroke and bleeding. The goal was to see if this approach is safer and more effective than standard blood-thinning medication…

This study looked at a procedure to close a small pouch in the heart (the left atrial appendage) in 58 people with an irregular heartbeat (atrial fibrillation) who had previously had a brain bleed. Because blood thinners, the usual treatment to prevent strokes, are too risky for …

This study looked at whether a procedure called cryoballoon ablation can safely treat atrial fibrillation (an irregular heartbeat) in people who also have severe heart failure. About 1,420 adults with both conditions received the freezing treatment to isolate the veins in the hea…

This study tested a new tool called VISITAG that helps doctors track where they apply heat during a heart procedure for atrial fibrillation (AFib). 200 people having their first ablation took part. The goal was to see if the tool made the procedure safer and better at preventing …

This study looked at whether using a CPAP machine during sleep can reduce episodes of atrial fibrillation (an irregular heart rhythm) in people who also have obstructive sleep apnea. Researchers measured changes in heart rhythm, heart size, quality of life, and hospital visits in…

This study tested a special catheter and generator system to treat paroxysmal atrial fibrillation (PAF), a condition where the heart beats irregularly. 135 adults with PAF that didn't improve with medication took part. The procedure uses heat energy to isolate the pulmonary veins…

This study looked at how well the blood thinner edoxaban works and its safety in people aged 80 and older with a type of irregular heartbeat called atrial fibrillation. Atrial fibrillation raises the risk of stroke, especially in older adults. The study followed over 1,200 patien…

This study enrolled 343 adults with atrial fibrillation to see if a team-based care program led by a heart rhythm specialist could help control the condition and uncover hidden risk factors. Participants received coordinated care from multiple specialists. The main goal was to me…

This study tested if closing a small heart pouch (left atrial appendage) with a device is safer and as effective as standard blood thinners for preventing strokes in people with atrial fibrillation who are also getting a new heart valve. About 80 participants were randomly assign…

This early-phase study tested whether placing a human amniotic membrane on the heart during bypass surgery could lower inflammation and reduce the chance of developing atrial fibrillation afterward. 27 adults having their first bypass surgery were randomly assigned to receive eit…

This study looked at how safe and effective a device called the Amplatzer Amulet is for closing a small pouch in the heart (left atrial appendage) in people with atrial fibrillation. The goal is to reduce the risk of stroke without needing lifelong blood thinners. The study inclu…

This study tested a device called the Lariat to close off a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who cannot take blood thinners. The goal was to reduce the risk of stroke caused by blood clots forming in that pouch. Nine patients…

This study looked at whether metformin, a common diabetes medicine, can help prevent atrial fibrillation (an irregular heartbeat) from coming back after a heart ablation procedure. Researchers enrolled 117 people with a BMI over 25 who were scheduled for ablation. Participants ei…

This study compared two treatments for persistent atrial fibrillation (an irregular heartbeat): a procedure that freezes heart tissue (cryoablation) versus standard antiarrhythmic drugs. 196 adults with recurrent persistent AF were randomly assigned to one treatment. The goal was…

This study looked at a new combination of two blood thinners, rivaroxaban and ticagrelor, in 40 people with atrial fibrillation who had a heart stent placed. The goal was to see if this combo causes less bleeding than the standard three-drug therapy, while still preventing heart …

This study tested whether a tailored ablation approach, which targets specific problem areas in the heart unique to each patient, works better than the standard anatomical ablation for treating persistent atrial fibrillation (AFib). 377 adults with AFib were enrolled. The goal wa…

This study tested a device called the Laminar Left Atrial Appendage Closure System in 29 adults with atrial fibrillation (an irregular heartbeat) who are at high risk for stroke but cannot take blood thinners. The device is placed to seal off a small pouch in the heart where clot…

This study tested a new method called pulsed field ablation against the standard radiofrequency ablation for people with a type of irregular heartbeat called paroxysmal atrial fibrillation. The goal was to see if the new method is faster, safer, and works better at stopping the i…

This study tested a new device called the DiamondTemp Ablation System to treat people with persistent atrial fibrillation (a type of irregular heartbeat) that medication couldn't control. Researchers wanted to see if the device could safely restore a normal heart rhythm for at le…

This study tested the safety and effectiveness of a new catheter system (OMNYPULSE with TRUPULSE generator) for treating paroxysmal atrial fibrillation, a type of irregular heartbeat. 188 participants underwent a procedure to isolate the pulmonary veins using this system. The mai…

This study tested a special balloon catheter that uses radiofrequency energy to treat people with a heart condition called paroxysmal atrial fibrillation (irregular heartbeat). The trial included 397 adults aged 18-75 who had not responded to medication. The goal was to see if th…

This study tested whether pharmacists can help older adults with atrial fibrillation (AF) take the right blood thinners to prevent strokes. Fourteen people aged 60 and older with AF and stroke risks took part. Pharmacists managed their medications for 3 months, and the team check…

This study tested a new computer tool (VX1) to guide repeat catheter ablation in 96 people with atrial fibrillation (AF) whose symptoms returned after a prior ablation. The goal was to see if targeting specific heart signals could keep the heart in normal rhythm for at least a ye…

This study tested whether closing off a small heart pouch (left atrial appendage) with the WATCHMAN FLX device is a safe and effective alternative to long-term blood thinners in people with atrial fibrillation who already had a catheter ablation. About 1,600 high-risk participant…

This study tested the WATCHMAN FLX Pro device in 949 people with atrial fibrillation (an irregular heartbeat) to see how well it prevents strokes. The device is implanted to close off a part of the heart where clots can form. Researchers measured safety and effectiveness in real-…

This study tested whether a newer blood thinner (rivaroxaban) is safer and more cost-effective than the standard drug warfarin for patients who develop atrial fibrillation after heart surgery. About 100 adults who had open-heart surgery and then experienced a new irregular heartb…

This study looked at 411 people with both heart failure and atrial fibrillation (a fast, irregular heartbeat). It compared two approaches: using a catheter ablation procedure to restore normal heart rhythm, versus simply controlling the heart rate with medication. The goal was to…

This study looked at 200 people with permanent atrial fibrillation (an irregular heartbeat) and heart failure (a weak heart pump). Researchers wanted to see if adding pacing to both lower heart chambers, along with a defibrillator, could shrink the heart's main pumping chamber an…

This study looked at 700 people with both atrial fibrillation (an irregular heartbeat) and heart failure (a weak heart pump). It compared two catheter-based treatments that isolate the veins carrying abnormal signals to the heart: a newer method called pulsed-field ablation and a…

This study looked at two different approaches for treating persistent atrial fibrillation (a long-lasting irregular heartbeat) using a procedure called catheter ablation. 480 adults were randomly assigned to either have the ablation aim to stop the irregular rhythm during the pro…

This study looked at over 3,000 people with atrial fibrillation who needed a heart procedure. It tested whether a simple score (ATE) using medical history and a blood test could safely rule out dangerous blood clots in the heart, avoiding the need for an uncomfortable ultrasound.…

This study tested whether a Withings device (BeamO with ECG app) can accurately detect atrial fibrillation, a common heart rhythm problem. Researchers compared the device's readings to a standard 12-lead ECG in 373 adults aged 22 and older. The goal was to see how well the device…

This study checked how well a new ECG device (Masimo INVSENSOR00057) measures heart rate and detects atrial fibrillation (AFib). It included 365 adults—some healthy and some with AFib. The goal was to see if the device works as well as standard ECG measurements.

This study tested whether an Apple Watch could help find a heart rhythm problem called atrial fibrillation (AF) earlier in people at high risk. Over 400 adults aged 65 and older with certain risk factors wore an Apple Watch to monitor their heart. The goal was to see if the watch…

This study tested a low-dose drug called landiolol to prevent atrial fibrillation (a type of irregular heartbeat) after heart surgery. About 400 non-Asian adults who had heart surgery took part. The goal was to see if landiolol could lower the chance of developing this complicati…

This study tested a new feature called FARAVIEW on a heart mapping system used with a special catheter to treat atrial fibrillation (an irregular heartbeat). Fifty adults with symptomatic AFib that didn't respond to medication took part. The goal was to see how well doctors could…

This study looked at how safe and effective a magnet-guided catheter is for treating atrial fibrillation, a condition causing an irregular heartbeat. Over 800 patients took part, and the procedure aimed to isolate faulty veins in the heart to restore normal rhythm. The approach f…

This study looked at whether a weight loss program could reduce symptoms of atrial fibrillation (an irregular heartbeat) in overweight adults aged 60 to 85. Participants either joined a diet and behavior support program or received usual care for about 8 months. The main goal was…

This study tested a mindfulness and exposure program in 13 adults with atrial fibrillation who also had high anxiety sensitivity. The goal was to see if the program could reduce heart-related anxiety, symptom burden, and AFib episodes. The approach combined mindfulness techniques…

This study tested whether showing patients with atrial fibrillation (AF) simple visual charts about common post-ablation symptoms helps them make more confident treatment decisions. 75 adults with symptomatic AF who were considering catheter ablation used these decision aids duri…

This study tested two different defibrillator waveforms (Zoll's 200J shock vs. Lifepak's 360J shock) to see which one better restores normal heart rhythm in people with atrial fibrillation. Over 500 adults participated, and the main goal was to check heart rhythm one minute after…

This study tested a virtual education program called "AF at Home" for adults with atrial fibrillation (AF). Participants attended six hours of online classes over three weeks and completed questionnaires before and after. The goal was to see if the program could improve quality o…

This study looked at people with persistent atrial fibrillation who had a heart ablation. Two months later, they had a second procedure to check for reconnections in the treated veins and fix them. The goal was to see if this approach leads to better long-term results and to lear…

This study aimed to create a new questionnaire that measures how atrial fibrillation (AF) affects a person's quality of life. Researchers worked with 206 people who have AF to develop and test this scale. The goal was to give doctors a better way to understand the real-world impa…

This study tested a new imaging system called VERAFEYE in 18 adults already scheduled for a standard heart procedure like ablation or closure. Doctors used the system and then gave feedback through a questionnaire. The goal was not to prove the system works or is safe, but to gat…

This study looked at over 12,500 people with atrial fibrillation (an irregular heartbeat) to see how their condition changed over time and how it related to serious events like stroke or bleeding. Researchers used existing hospital and national insurance records in Korea, so no n…

This study tested whether a special heart map (isochron map) can predict if atrial fibrillation will return after a standard treatment called radiofrequency ablation. Researchers followed 175 adults for 18 months to see who had a relapse. The goal was to find better ways to forec…

This study looked at whether notifying a pharmacist about a risky blood thinner prescription works better than notifying the doctor. Researchers tested two types of alerts with 306 prescribers and pharmacists. The goal was to see which method led to faster and more frequent presc…

This study looked at 516 people who had a transient ischemic attack (TIA or mini-stroke) to find the best way to detect atrial fibrillation (AF), a heart rhythm problem that raises stroke risk. Participants used either a 24-hour ECG, a 28-day wearable ECG monitor, or a small impl…

This study tested a new computer algorithm that measures electrical signals in the heart during a procedure to treat atrial fibrillation (AFib). 21 adults with persistent AFib took part. The goal was to see if the algorithm could help doctors better understand the heart's rhythm …

This study tested whether a computer program (Clinical Decision Support System) helps doctors follow official treatment guidelines for patients with both high blood pressure and atrial fibrillation. About 282 patients took part, and doctors were split into two groups: one using t…

This study gathered information from 100 people undergoing a standard heart procedure to close a small pouch in the heart (left atrial appendage). Researchers used routine scans to see if a new software tool can measure the pouch as accurately as a CT scan. No extra tests or trea…

This study looked back at health records of over 2 million people in France with atrial fibrillation (an irregular heartbeat) between 2016 and 2020. Researchers compared those who took blood thinners (oral anticoagulants) to those who did not, to see how many had strokes, major b…

This study followed 1826 people who already needed a small heart monitor (Confirm Rx) to check for irregular heartbeats. Over 12 months, researchers collected real-world data to see how safe and well the device worked. The goal was to confirm its performance outside of a controll…

This study looked at two methods for assigning care coordinators to older adults (65+) who have heart disease or related risks like diabetes or high blood pressure. The goal was to see which method better prevents emergency room visits and hospital stays. Researchers compared ass…

This small pilot study looked at 5 adults without atrial fibrillation but with other stroke risk factors. Researchers used advanced heart imaging and brain MRIs to see if heart abnormalities are linked to silent, unnoticed strokes. The goal is to better identify who might benefit…

This study tested a 12-week virtual education program for primary care providers in North Carolina to improve how they manage patients with atrial fibrillation (an irregular heartbeat). 70 providers joined the program, and researchers measured changes in their knowledge and confi…

This study looked at 167 adults with atrial fibrillation or flutter who were scheduled for their first catheter ablation. Researchers measured stroke and bleeding risk scores before the procedure and again at 3, 6, and 12 months after. They also used heart monitors and smartwatch…

This study gathered information from routine medical care for 198 adults with atrial fibrillation who already had a device to close off a part of the heart (left atrial appendage occlusion) and then later underwent a heart ablation procedure. Researchers looked at patient details…

This study looked at 155 people with early-onset atrial fibrillation (a heart rhythm problem) to see how their genes might affect their condition. Participants had genetic testing and then underwent heart scans, ECGs, and monitoring. The goal was to find inherited heart condition…

This study looked at 309 older adults with a type of heart failure called HFpEF to understand why some develop atrial fibrillation (AFib), an irregular heartbeat. Researchers measured fluid pressure in the body and brain using ultrasound and found that higher pressure in the vein…

This study looked at how safe and effective Trombix® (Rivaroxaban) is for people with atrial fibrillation (an irregular heartbeat) in everyday medical practice in Algeria. Researchers tracked 398 patients to see how many had serious bleeding side effects and how the treatment aff…

This study tested a larger 31 mm cryoballoon in 20 patients with paroxysmal atrial fibrillation to see how much heart tissue it could ablate. Researchers used 3D maps before and after the procedure to measure the treated area. The goal was to gather data to improve future ablatio…

This study involved 13 adults with atrial fibrillation whose doctors chose rate control as their treatment approach. Researchers tested whether changing medication doses affected how much oxygen patients used during exercise, aiming to find the best marker for rate control. The s…

This study looked at 50 adults with atrial fibrillation (an irregular heartbeat) to see if special heart scans and ECGs could predict whether the drug flecainide would help them. Researchers followed participants for 12 months, collecting data during four visits. The goal is to r…

This study looked at 200 people with atrial fibrillation to see how two treatments—catheter ablation or exercise training—change levels of a brain chemical called BDNF. Researchers also checked if these changes relate to depression, quality of life, and symptoms. The goal was to …

This study looked at whether stopping coffee drinking can reduce the chance of atrial fibrillation (an irregular heartbeat) returning after a procedure called cardioversion. About 200 adults who drank at least one cup of coffee daily were randomly assigned to either quit or keep …