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Can extra pacing shrink an enlarged heart? new study explores

NCT ID NCT01994252

First seen May 01, 2026 · Last updated May 19, 2026 · Updated 6 times

Summary

This study looked at 200 people with permanent atrial fibrillation (an irregular heartbeat) and heart failure (a weak heart pump). Researchers wanted to see if adding pacing to both lower heart chambers, along with a defibrillator, could shrink the heart's main pumping chamber and improve function. Participants already had a defibrillator and were followed to measure survival, heart failure events, heart size, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHUM Centre hospitalier universitaire de Montréal

    Montreal, Quebec, Canada

  • Hamilton Health Sciences

    Hamilton, Ontario, Canada

  • Institut universitaire de cardiologie et de pneumologie de Quebec

    Québec, Quebec, Canada

  • Kingston General Hospital

    Kingston, Ontario, Canada

  • Le Centre hospitalier universitaire de Sherbrooke

    Sherbrooke, Quebec, Canada

  • Libin Cardiovascular Institute of Alberta

    Calgary, Alberta, Canada

  • London Health Sciences Centre

    London, Ontario, N6A 5A5, Canada

  • McGill Health Science Centre

    Montreal, Quebec, Canada

  • Montreal Heart Institute

    Montreal, Quebec, Canada

  • Queen Elizabeth II Health Science

    Halifax, Nova Scotia, Canada

  • St. Boniface General Hospital

    Winnipeg, Manitoba, Canada

  • St. Michael's General Hospital

    Toronto, Ontario, Canada

  • University of Ottawa Heart Institute

    Ottawa, Ontario, K1W 4W7, Canada

  • Vancouver General Hospital

    Vancouver, British Columbia, Canada

  • Victoria Cardiac Arrhythmia Trials

    Victoria, British Columbia, V8R 4R2, Canada

Conditions

Explore the condition pages connected to this study.