HEART DISEASE

This study aims to see if giving people healthy prepared meals and education helps them eat better compared to just physical activity coaching. It involves 120 adults in Anson County who have or are at risk for chronic conditions like obesity, diabetes, or heart disease. Particip…

This study is testing a new device called the Supira System in 45 people with heart failure and severe coronary artery disease who need a high-risk heart procedure. The device helps pump blood during and after the procedure, potentially reducing complications. The goal is to see …

This study looks at whether training doctors to quickly start and adjust four types of heart failure medications while patients are still in the hospital leads to better long-term treatment. About 438 adults with heart failure and reduced pumping ability will take part. The goal …

This study tests whether giving families access to healthy food, online tools, and personal health coaching can improve heart health and encourage lasting lifestyle changes. About 120 families, each with one parent who has a BMI over 30 and a child aged 6 to 11, will be assigned …

This study tests a drug called orticumab in 240 people who have had a heart attack and still have high inflammation in their heart arteries. The goal is to see if orticumab can lower this inflammation better than a placebo over 6 months. Participants will have CT scans to measure…

This study checks if a chest-patch that measures blood pressure without a cuff is as accurate as the standard arm-cuff method over 24 hours. About 600 adults with or without high blood pressure will wear both devices. The goal is to see if the patch is reliable and easier to use.

This study tests whether using artificial intelligence (AI) to read heart tests (ECG and ultrasound) can find heart disease in people who don't know they have it. About 19,300 participants, including teens, adults, and pregnant women, will get quick AI results. The goal is to see…

This study aims to help Latino families in San Diego and Mexicali become more physically active to prevent obesity and heart disease. About 290 parents and children ages 6-11 will take part in community-based programs. Researchers will measure activity levels and fitness to see i…

This study tests whether a smartphone app (DigitHeart-2) can accurately predict heart structure and function from a photo of an ECG. About 478 adults who are already scheduled for an echocardiogram will participate. Researchers will compare the app's predictions to the standard u…

This study follows 750 people with sickle cell disease to see if curative treatments like stem cell transplants improve or harm the heart, lungs, and kidneys over time. Researchers will compare those who received curative therapy with those on standard care. The goal is to help p…

This study collects genetic and health information from 3,000 people to help doctors choose the right medications and avoid side effects. Participants include those taking multiple medications or specific drugs for blood pressure or depression. The goal is to learn how genes affe…

This study looks at how men and women differ in staying physically active during and after cardiac rehabilitation. Researchers will track steps and fitness levels in 150 adults over 10 months. The goal is to understand barriers to exercise and help improve long-term heart health …

This early study tests if a special ultrasound contrast agent (microbubbles) can measure pressure inside the heart without using a catheter. Ten adults with suspected heart disease will receive the contrast agent and have their heart scanned. Researchers will compare the microbub…

This study looks at a tool called Transit-Time Flow Measurement (TTFM) that uses sound waves during heart bypass surgery to check blood flow through new blood vessels. The goal is to see if using this tool helps prevent the new vessels from failing. About 1242 adults having their…

This study looks at how a person's genes and their environment (like pollution, diet, and lifestyle) work together to cause common diseases such as diabetes, heart disease, and asthma. Researchers are collecting health questionnaires and genetic data from 25,000 adults to build a…