New drug aims to cool heart inflammation after heart attack

NCT ID NCT06927739

Recruiting now Disease control Sponsor: Abcentra Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 26 times

Summary

This study tests a drug called orticumab in 240 people who have had a heart attack and still have high inflammation in their heart arteries. The goal is to see if orticumab can lower this inflammation better than a placebo over 6 months. Participants will have CT scans to measure inflammation levels. This is a Phase 2 trial, meaning it's still early in testing for safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Abcentra Investigational Site
NOT_YET_RECRUITING

Los Angeles, California, 90048, United States
Abcentra Investigational Site
RECRUITING

Torrance, California, 90502, United States
Abcentra Investigational Site
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Boca Raton, Florida, 33434, United States
Abcentra Investigational Site
RECRUITING

Richmond, Indiana, 47374, United States
Abcentra Investigational Site
NOT_YET_RECRUITING

Louisville, Kentucky, 40202, United States
Abcentra Investigational Site
RECRUITING

Baltimore, Maryland, 21215, United States
Abcentra Investigational Site
RECRUITING

Midland, Michigan, 48670, United States
Abcentra Investigational Site
RECRUITING

Ostrava, Moravian-Silesian Region, 728 80, Czechia
Abcentra Investigational Site
RECRUITING

Pilsen, Plzeň Region, 323 00, Czechia
Abcentra Investigational Site
RECRUITING

Prague, Praha 2, 128 08, Czechia
Abcentra Investigational Site
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Prague, Praha 4, 140 21, Czechia
Abcentra Investigational Site
RECRUITING

Brno, South Moravian, 602 00, Czechia
Abcentra Investigational Site
RECRUITING

Pécs, Baranya, 7635, Hungary
Abcentra Investigational Site
RECRUITING

Budapest, Central Hungary, 1036, Hungary
Abcentra Investigational Site
RECRUITING

Budapest, Central Hungary, 1094, Hungary
Abcentra Investigational Site
RECRUITING

Budapest, Central Hungary, 1132, Hungary
Abcentra Investigational Site
RECRUITING

Nyíregyháza, Szabolcs-Szatmár-Bereg, 4400, Hungary
Abcentra Investigational Site
RECRUITING

Caserta, Campania, 81100, Italy
Abcentra Investigational Site
RECRUITING

Ferrara, Ferrara, 44124, Italy
Abcentra Investigational Site
RECRUITING

Brescia, Lombardy, 25123, Italy
Abcentra Investigational Site
RECRUITING

Milan, Lombardy, 20162, Italy
Abcentra Investigational Site
RECRUITING

Pavia, Lombardy, 27100, Italy
Abcentra Investigational Site
RECRUITING

Krakow, Lesser Poland Voivodeship, 30-082, Poland
Abcentra Investigational Site
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 50-556, Poland
Abcentra Investigational Site
RECRUITING

Warsaw, Masovian Voivodeship, 03-505, Poland
Abcentra Investigational Site
RECRUITING

Baia Mare, Maramureş, 430031, Romania
Abcentra Investigational Site
RECRUITING

Târgu Mureş, Mureș County, 540124, Romania
Abcentra Investigational Site
RECRUITING

Timișoara, Timiș County, 300060, Romania
Abcentra Investigational Site
RECRUITING

Córdoba, Andalusia, 14004, Spain
Abcentra Investigational Site
RECRUITING

Madrid, Madrid, 28034, Spain
Abcentra Investigational Site
RECRUITING

Madrid, Madrid, 28046, Spain
Abcentra Investigational Site
RECRUITING

El Palmar, Murcia, 30120, Spain
Abcentra Investigational Site
RECRUITING

Seville, Sevilla, 41009, Spain
Abcentra Investigational Site
RECRUITING

Danderyd, Stockholm County, 182 88, Sweden
Abcentra Investigational Site
RECRUITING

Solna, Stockholm County, 171 76, Sweden
Abcentra Investigational Site
RECRUITING

Gothenburg, Västra Götaland County, 413 45, Sweden
Abcentra Investigational Site
RECRUITING

London, Greater London, EC1M 6BQ, United Kingdom
Abcentra Investigational Site
RECRUITING

Manchester, Greater Manchester, M23 9LT, United Kingdom
Abcentra Investigational Site
RECRUITING

Oxford, Oxfordshire, OX3 9DU, United Kingdom
Abcentra Investigational Site
RECRUITING

Bath, Somerset, BA1 3NG, United Kingdom
Abcentra Investigational Site
RECRUITING

Sheffield, South Yorkshire, S57AU, United Kingdom

Conditions

Explore the condition pages connected to this study.

ACUTE CORONARY SYNDROMES ACUTE CORONARY SYNDROMES ATHEROSCLEROTIC CORONARY VASCULAR DISEASE CORONARY ARTERIAL DISEASE (CAD) HEART DISEASE INFLAMMATION MYOCARDIAL INFARCT MYOCARDIAL INFARCT