Can a pacemaker improve life for those with two common heart conditions?

NCT ID NCT01994252

First seen May 01, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study looked at whether adding a special pacemaker (called biventricular pacing) to an implantable defibrillator can help people who have both permanent atrial fibrillation and heart failure. The goal was to see if this treatment could shrink an enlarged heart, improve its pumping ability, and reduce symptoms like shortness of breath and swelling. The study enrolled 200 adults with moderate heart failure symptoms who were already candidates for a defibrillator.

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Contacts and locations

Locations

  • CHUM Centre hospitalier universitaire de Montréal

    Montreal, Quebec, Canada

  • Hamilton Health Sciences

    Hamilton, Ontario, Canada

  • Institut universitaire de cardiologie et de pneumologie de Quebec

    Québec, Quebec, Canada

  • Kingston General Hospital

    Kingston, Ontario, Canada

  • Le Centre hospitalier universitaire de Sherbrooke

    Sherbrooke, Quebec, Canada

  • Libin Cardiovascular Institute of Alberta

    Calgary, Alberta, Canada

  • London Health Sciences Centre

    London, Ontario, N6A 5A5, Canada

  • McGill Health Science Centre

    Montreal, Quebec, Canada

  • Montreal Heart Institute

    Montreal, Quebec, Canada

  • Queen Elizabeth II Health Science

    Halifax, Nova Scotia, Canada

  • St. Boniface General Hospital

    Winnipeg, Manitoba, Canada

  • St. Michael's General Hospital

    Toronto, Ontario, Canada

  • University of Ottawa Heart Institute

    Ottawa, Ontario, K1W 4W7, Canada

  • Vancouver General Hospital

    Vancouver, British Columbia, Canada

  • Victoria Cardiac Arrhythmia Trials

    Victoria, British Columbia, V8R 4R2, Canada

Conditions

Explore the condition pages connected to this study.