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Heart ablation after pouch closure: new registry data collected

NCT ID NCT07580937

Knowledge-focused Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study gathered information from routine medical care for 198 adults with atrial fibrillation who had a prior procedure to close a small heart pouch (left atrial appendage occlusion) and later needed a heart ablation. Researchers looked at patient details, procedure steps, blood thinner use after the procedure, and any complications. The goal was to better understand how to manage these complex cases, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

198 people

The number who actually took part.

Started

Mar 2022

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals aged \>18 years * Undergoing any type of atrial fibrillation ablation or left atrial arrhythmia ablation Exclusion Criteria: * Missing essential baseline characteristics and/or missing collection of sufficient details regarding each complication

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial arrhythmia Atrial fibrillation

Contacts and locations

Locations

  • Asian Heart and Vascular Center

    Singapore, Singapore

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cardioangiologisches Centrum Bethanien Frankfurt

    Frankfurt, Germany

  • Clinique Pasteur

    Toulouse, France

  • Loyola University

    Chicago, Illinois, 60660, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Nanjing Medical University

    Nanjing, China

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • OLV Hospital

    Aalst, Belgium

  • Ospedali Riuniti Umberto I°-Lancisi-Salesi

    Ancona, Italy

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • University Hospital Basel

    Basel, Switzerland

  • University Hospital of Bern

    Bern, Switzerland

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Liverpool

    Liverpool, United Kingdom

  • University of Lübeck

    Lübeck, Germany

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

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