Could a cancer drug fix an irregular heartbeat?
NCT ID NCT03298321
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether Vidaza, a drug used for acute leukemia, could also help treat atrial fibrillation (an irregular heartbeat). The idea was that Vidaza might reverse certain DNA changes that lower the activity of a gene important for heart function. Only one person took part, and researchers tracked heart rhythm and heart structure changes over 6 to 12 months.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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1 person
The number who actually took part.
- Started
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Dec 2018
- Finished
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Dec 2018
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will be performed on adults with Acute Myeloid Leukemia and atrial fibrillation. Only patients treated for the first time with vidaza® within an hospital hematology unit will be included.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years old * Patient with history of paroxysmal atrial fibrillation, and /or presenting a dilatation of the left atrium. * Patient selected for a first Vidaza® treatment * Non-opposition of the patient to participate in the study Exclusion Criteria: * Age \< 18 years old * No paroxysmal atrial fibrillation * Patients with previous history of Vidaza® treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Léon Berard
Lyon, 69008, France
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Hopital Lyon Sud
Pierre-Bénite, 69310, France
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Service de rythmologie - GH Est-Hôpital Louis Pradel - CHU de Lyon HCL
Bron, 69229, France
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