University Hospital, Bordeaux

This study aims to see if a sample of bile (a fluid made by the liver) can be used to accurately diagnose cholangiocarcinoma, a type of bile duct cancer. Researchers will compare results from bile samples with standard tissue biopsies in 200 adults who already need a procedure fo…

This study aims to develop a blood test that uses fetal DNA found in the mother's blood to determine paternity early in pregnancy (6 to 22 weeks). It is designed for cases of sexual assault where the father is unknown, helping to reduce uncertainty and trauma. The test will be us…

This study looks at how hormone replacement therapy (HRT) changes sexual quality of life in women with premature ovarian failure (early menopause). About 135 women will fill out a questionnaire before and 6 months after starting HRT. The goal is to see if HRT helps improve sexual…

This study looks at how small vessel disease in the brain affects thinking skills like memory and attention. Researchers will measure brain activity using EEG in 80 older adults and test whether personalized computer-based brain training or gentle electrical stimulation can help.…

This study aims to learn how much transgender people in France know about gynecological care and cancer screening. Researchers will survey 500 transgender adults to understand their awareness of health recommendations. The goal is to improve care for this community.

This study tests a new, faster ultrasound method to measure heart stiffness and blood flow in children with congenital heart disease. Current tools don't assess heart filling well in kids, limiting treatment. Researchers will compare this new technique with standard ultrasound in…

This study looks at whether multiple sclerosis (MS) affects a woman's ovarian reserve—the number of eggs she has left. Researchers will compare blood tests and ultrasound results from 160 women aged 25 to 35, half with MS and half without. The goal is to understand if MS itself i…

This study looks at whether starting dialysis earlier or later helps patients with tumor lysis syndrome (a complication from cancer treatment) who also have sudden kidney injury. Researchers will compare kidney function 30 days after treatment in 800 adults. The goal is to find t…

This study looks at how mitochondrial diseases can weaken the immune system. Researchers will measure immune cells and antibodies in 60 people with confirmed mitochondrial disease. The goal is to better understand these immune problems, which could lead to better diagnosis and ne…

This study tests whether adding a nailfold capillaroscopy (a quick, painless microscope exam of tiny blood vessels at the base of fingernails) to standard care helps doctors diagnose connective tissue disease sooner in people newly diagnosed with interstitial lung disease. About …

This study looks at whether using specially treated water in reusable bottles for colonoscopy is safe and better for the environment. Researchers will check if the water gets contaminated with germs from the patient during the procedure. They will also measure how much extra work…

This study aims to understand how cortisol and other steroid hormones are produced over 24 hours in people with adrenal gland tumors. Researchers will use a special device to take fluid samples every 20 minutes for 1-2 days from 40 participants. The goal is to compare hormone pat…

This study looks at a blood test that may help doctors decide which children with shock after heart surgery truly need extra fluids. Giving fluids when not needed can cause harm, so finding the right marker is important. About 110 children in intensive care will be enrolled to se…