University Hospital, Bordeaux

This study tests whether adding metformin, a common diabetes drug, to the standard rheumatoid arthritis (RA) medication methotrexate helps more people achieve disease control. About 128 adults with active RA who have not recently taken methotrexate will receive either methotrexat…

This study tests a combination of two drugs (spartalizumab and low-dose pazopanib) in 80 children and adults whose solid tumors have not responded to standard treatments. The goal is to see if the combo can shrink or stabilize the cancer for at least 6 months. The pediatric part …

This study tests whether adding an anti-TNF drug to baricitinib works better than baricitinib alone for people with rheumatoid arthritis that hasn't responded well to other treatments. About 160 adults with active RA will be randomly assigned to one of the two treatment groups. T…

This study tests whether virtual reality exposure therapy can help people who had bariatric surgery feel better about their body image. It includes 11 participants who are 18 to 30 months post-surgery and unhappy with their appearance. The approach uses VR sessions to address bod…

This study looks at 500 adults with lupus to see if certain immune system markers can better predict who is at high risk for heart disease. Researchers will track changes in artery health over time using ultrasound. The goal is to improve heart risk assessment for people with lup…

This study looks at whether routine screening for heart disease is a good use of healthcare money for people with type 2 diabetes who are at very high risk but have no known heart problems. Researchers will analyze data from 90,000 patients in French health databases to compare c…

This study is for adults receiving a kidney, lung, liver, or heart transplant. It will collect blood and tissue samples to learn how the body responds to CMV, a common virus that can cause serious problems after transplant. The goal is to better understand the virus and improve f…

This study follows 66 people with primary progressive multiple sclerosis (PPMS) and healthy volunteers over 2 years to understand how thinking skills change. Researchers use memory and attention tests along with advanced brain scans to see which brain changes cause cognitive prob…

This study looks back at 46 adults with non-small-cell lung cancer that has spread only to the brain (fewer than 5 spots). Researchers want to see which treatment strategies worked best by tracking how long patients stayed free of cancer growth. The goal is to find a standard app…